Retention and bandwidths prediction in fast gradient liquid chromatography. Part 2-Core-shell columns

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F14%3A39901112" target="_blank" >RIV/00216275:25310/14:39901112 - isvavai.cz</a>

Výsledek na webu

<a href="http://apps.webofknowledge.com/full_record.do?product=UA&search_mode=CitationReport&qid=2&SID=Z1SlQQ96mtHfGpISes8&page=2&doc=15" target="_blank" >http://apps.webofknowledge.com/full_record.do?product=UA&search_mode=CitationReport&qid=2&SID=Z1SlQQ96mtHfGpISes8&page=2&doc=15</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chroma.2014.02.023" target="_blank" >10.1016/j.chroma.2014.02.023</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Retention and bandwidths prediction in fast gradient liquid chromatography. Part 2-Core-shell columns

Popis výsledku v původním jazyce

Recently, we confirmed that the well-established theory of gradient elution can be employed for prediction of retention in gradient elution from the isocratic data, method development and optimization in fast gradient chromatography employing short packed fully porous and monolithic columns and gradient times in between 1 and 2 min, or even less. In the present work, we extended this study to short core-shell reversed-phase columns. We investigated the effects of the specification of the stationary phase in the core-shell structure on the prediction of gradient retention data. Two simple retention models describing the effects of the mobile phase on the retention by two-parameter equations yield comparable accuracy and can be used for prediction of elution times. The log-log model provides improved prediction of gradient bandwidths, especially for less retained compounds. A more sophisticated three-parameter model did not offer significant improvement of prediction. We compared the eff

Název v anglickém jazyce

Retention and bandwidths prediction in fast gradient liquid chromatography. Part 2-Core-shell columns

Popis výsledku anglicky

Recently, we confirmed that the well-established theory of gradient elution can be employed for prediction of retention in gradient elution from the isocratic data, method development and optimization in fast gradient chromatography employing short packed fully porous and monolithic columns and gradient times in between 1 and 2 min, or even less. In the present work, we extended this study to short core-shell reversed-phase columns. We investigated the effects of the specification of the stationary phase in the core-shell structure on the prediction of gradient retention data. Two simple retention models describing the effects of the mobile phase on the retention by two-parameter equations yield comparable accuracy and can be used for prediction of elution times. The log-log model provides improved prediction of gradient bandwidths, especially for less retained compounds. A more sophisticated three-parameter model did not offer significant improvement of prediction. We compared the eff

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/GAP206%2F12%2F0398" target="_blank" >GAP206/12/0398: Dvourozměrné separace v kapalných médiích</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Chromatography A

ISSN

0021-9673

e-ISSN

—

Svazek periodika

1337

Číslo periodika v rámci svazku

April

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

10

Strana od-do

57-66

Kód UT WoS článku

000334082200009

EID výsledku v databázi Scopus

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