Compressibility of tableting materials and properties of tablets with glyceryl behenate

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F15%3A39899505" target="_blank" >RIV/00216275:25310/15:39899505 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11160/15:10312215

Výsledek na webu

<a href="http://dx.doi.org/10.1515/acph-2015-0006" target="_blank" >http://dx.doi.org/10.1515/acph-2015-0006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/acph-2015-0006" target="_blank" >10.1515/acph-2015-0006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Compressibility of tableting materials and properties of tablets with glyceryl behenate

Popis výsledku v původním jazyce

The paper studies the compressibility of directly compressible tableting materials with dry binders, spray-dried lactose and microcrystalline cellulose, and glyceryl dibehenate at various concentrations. Compressibility was evaluated by means of the energy profile of compression and tensile strength of tablets. Release rate of the active ingredient, salicylic acid, from the tablets was also examined. In the case of microcrystalline cellulose, a higher concentration of glyceryl dibehenate increased the strength of tablets, while this did not occur in the case of spray-dried lactose. Increasing concentration of glyceryl dibehenate prolonged the release of salicylic acid; however, no statistically significant difference was found compared to the type of the dry binder used.

Název v anglickém jazyce

Compressibility of tableting materials and properties of tablets with glyceryl behenate

Popis výsledku anglicky

The paper studies the compressibility of directly compressible tableting materials with dry binders, spray-dried lactose and microcrystalline cellulose, and glyceryl dibehenate at various concentrations. Compressibility was evaluated by means of the energy profile of compression and tensile strength of tablets. Release rate of the active ingredient, salicylic acid, from the tablets was also examined. In the case of microcrystalline cellulose, a higher concentration of glyceryl dibehenate increased the strength of tablets, while this did not occur in the case of spray-dried lactose. Increasing concentration of glyceryl dibehenate prolonged the release of salicylic acid; however, no statistically significant difference was found compared to the type of the dry binder used.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Pharmaceutica

ISSN

1330-0075

e-ISSN

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Svazek periodika

65

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

HR - Chorvatská republika

Počet stran výsledku

8

Strana od-do

91-98

Kód UT WoS článku

000350879000009

EID výsledku v databázi Scopus

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