The impact of Intra-luminal Thrombus failure on the mechanical stress in the wall of Abdominal Aortic Aneurysms
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F11%3APU93036" target="_blank" >RIV/00216305:26210/11:PU93036 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
The impact of Intra-luminal Thrombus failure on the mechanical stress in the wall of Abdominal Aortic Aneurysms
Popis výsledku v původním jazyce
The role of the Intra-luminal Thrombus (ILT) in Abdominal Aortic Aneurysm (AAA) rupture is controversial and it is still not clear if an ILT increases or decreases AAA rupture risk. Specifically, signs of bleeding in the ILT are thought to increase AAA rupture risk. In order to further investigate this hypothesis, intact AAAs (n=4) with clear signs of ILT rupture in Computer Tomography Angiography (CT-A) images were investigated. To this end two cases were investigated: an ILT failure extracted directlyfrom the CT-A data and a hypothetical ILT fissure connecting the lumen with the underlying aneurysm wall. Wall stress distributions were predicted based on the detailed Finite Element (FE) models. The study showed that the ILT rupture, as extracted fromthe CT-A data, can increase the mechanical stress in the underlying wall by up to 30%. The largest impact on the wall stress was observed if the ILT failure reaches the aneurysm wall or if it involves large parts of the ILT. In contrast,
Název v anglickém jazyce
The impact of Intra-luminal Thrombus failure on the mechanical stress in the wall of Abdominal Aortic Aneurysms
Popis výsledku anglicky
The role of the Intra-luminal Thrombus (ILT) in Abdominal Aortic Aneurysm (AAA) rupture is controversial and it is still not clear if an ILT increases or decreases AAA rupture risk. Specifically, signs of bleeding in the ILT are thought to increase AAA rupture risk. In order to further investigate this hypothesis, intact AAAs (n=4) with clear signs of ILT rupture in Computer Tomography Angiography (CT-A) images were investigated. To this end two cases were investigated: an ILT failure extracted directlyfrom the CT-A data and a hypothetical ILT fissure connecting the lumen with the underlying aneurysm wall. Wall stress distributions were predicted based on the detailed Finite Element (FE) models. The study showed that the ILT rupture, as extracted fromthe CT-A data, can increase the mechanical stress in the underlying wall by up to 30%. The largest impact on the wall stress was observed if the ILT failure reaches the aneurysm wall or if it involves large parts of the ILT. In contrast,
Klasifikace
Druh
J<sub>x</sub> - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)
CEP obor
BO - Biofyzika
OECD FORD obor
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Návaznosti výsledku
Projekt
<a href="/cs/project/GA106%2F09%2F1732" target="_blank" >GA106/09/1732: VÍCEÚROVŇOVÉ MODELOVÁNÍ CHOVÁNÍ HYPERELASTICKÝCH ANIZOTROPNÍCH MATERIÁLŮ</a><br>
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2011
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
ISSN
1078-5884
e-ISSN
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Svazek periodika
41
Číslo periodika v rámci svazku
4
Stát vydavatele periodika
GB - Spojené království Velké Británie a Severního Irska
Počet stran výsledku
7
Strana od-do
467-473
Kód UT WoS článku
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EID výsledku v databázi Scopus
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