Methodology for the optimization of LIBS analysis of soft tissues

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26210%2F19%3APU133527" target="_blank" >RIV/00216305:26210/19:PU133527 - isvavai.cz</a>

Výsledek na webu

<a href="https://emslibs.com/wp-content/uploads/2019/09/b3.2.pdf" target="_blank" >https://emslibs.com/wp-content/uploads/2019/09/b3.2.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Methodology for the optimization of LIBS analysis of soft tissues

Popis výsledku v původním jazyce

Biological tissues contain essential trace elements, such as Zn, Cu, Fe, which are known to have an important role in various metabolic processes taking place in the human body. The optimum level of concentration of these elements is needed to maintain the proper function and health of the human body [1]. In this work, we focused on the optimization of laserinduced breakdown spectroscopy (LIBS) methods used for a detection of these elements in soft tissues. Analysis of such samples using LIBS could be used for numerous biological applications in the future, such as the utilization of listed trace metals as the potential biomarkers for cancer tissue diagnostics [2, 3]. Laser-induced breakdown spectroscopy was applied to perform the elemental analysis of soft tissue samples – mouse kidneys. In order to get the optimum signal in the multi-element LIBS measurements of kidneys, the following experimental parameters: side input slit, grating, central wavelength, gate delay, laser energy, and wavelength were

Název v anglickém jazyce

Methodology for the optimization of LIBS analysis of soft tissues

Popis výsledku anglicky

Biological tissues contain essential trace elements, such as Zn, Cu, Fe, which are known to have an important role in various metabolic processes taking place in the human body. The optimum level of concentration of these elements is needed to maintain the proper function and health of the human body [1]. In this work, we focused on the optimization of laserinduced breakdown spectroscopy (LIBS) methods used for a detection of these elements in soft tissues. Analysis of such samples using LIBS could be used for numerous biological applications in the future, such as the utilization of listed trace metals as the potential biomarkers for cancer tissue diagnostics [2, 3]. Laser-induced breakdown spectroscopy was applied to perform the elemental analysis of soft tissue samples – mouse kidneys. In order to get the optimum signal in the multi-element LIBS measurements of kidneys, the following experimental parameters: side input slit, grating, central wavelength, gate delay, laser energy, and wavelength were

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů