3D-bioprinted Gelatin/Alginate loaded with Carbon Nanotubes for tissue engineering application

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F24%3APU151604" target="_blank" >RIV/00216305:26220/24:PU151604 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.eeict.cz/download" target="_blank" >https://www.eeict.cz/download</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

3D-bioprinted Gelatin/Alginate loaded with Carbon Nanotubes for tissue engineering application

Popis výsledku v původním jazyce

The objective of utilizing 3D-bioprinted Gelatin/Alginate loaded with Carbon Nanotubes (CNTs) in tissue engineering applications is to create scaffolds that closely mimic the natural extracellular matrix (ECM), thereby enhancing cell growth, proliferation, and differentiation. Gelatin and Alginate, both biocompatible materials, have been widely researched for their potential in bioprinting due to their similarity to the ECM, offering a conducive environment for cell encapsulation and tissue regeneration. The addition of CNTs to these hydrogels significantly improves the mechanical properties and stability of the scaffolds, making them more suitable for supporting tissue development. CNTs, known for their unique properties such as high tensile strength and electrical conductivity, contribute to the development of scaffolds that not only support mechanical stability but also can influence cellular behavior and tissue formation. This integration aims at enhancing the functionality of 3D-bioprinted scaffolds, enabling them to better support the formation and maturation of engineered tissues. Furthermore, the electrical conductivity of CNTs-loaded scaffolds can be exploited to stimulate electrical activity in tissues, such as cardiac and neural tissues, promoting organized tissue development and functionality. The strategic combination of Gelatin/Alginate with CNTs in 3D bioprinting offers a promising approach to tissue engineering, aiming to address the critical challenge of replicating the complex structure and function of natural tissues. This innovative methodology not only enhances the mechanical and structural properties of the scaffolds but also introduces new possibilities in tissue engineering through the electrical stimulation of tissues, paving the way for the creation of more complex and functional tissue constructs.

Název v anglickém jazyce

3D-bioprinted Gelatin/Alginate loaded with Carbon Nanotubes for tissue engineering application

Popis výsledku anglicky

The objective of utilizing 3D-bioprinted Gelatin/Alginate loaded with Carbon Nanotubes (CNTs) in tissue engineering applications is to create scaffolds that closely mimic the natural extracellular matrix (ECM), thereby enhancing cell growth, proliferation, and differentiation. Gelatin and Alginate, both biocompatible materials, have been widely researched for their potential in bioprinting due to their similarity to the ECM, offering a conducive environment for cell encapsulation and tissue regeneration. The addition of CNTs to these hydrogels significantly improves the mechanical properties and stability of the scaffolds, making them more suitable for supporting tissue development. CNTs, known for their unique properties such as high tensile strength and electrical conductivity, contribute to the development of scaffolds that not only support mechanical stability but also can influence cellular behavior and tissue formation. This integration aims at enhancing the functionality of 3D-bioprinted scaffolds, enabling them to better support the formation and maturation of engineered tissues. Furthermore, the electrical conductivity of CNTs-loaded scaffolds can be exploited to stimulate electrical activity in tissues, such as cardiac and neural tissues, promoting organized tissue development and functionality. The strategic combination of Gelatin/Alginate with CNTs in 3D bioprinting offers a promising approach to tissue engineering, aiming to address the critical challenge of replicating the complex structure and function of natural tissues. This innovative methodology not only enhances the mechanical and structural properties of the scaffolds but also introduces new possibilities in tissue engineering through the electrical stimulation of tissues, paving the way for the creation of more complex and functional tissue constructs.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

10601 - Cell biology

Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

proceedings I of the 30th student EEICT 2024

ISBN

978-80-214-6231-1

ISSN

2788-1334

e-ISSN

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Počet stran výsledku

3

Strana od-do

194-196

Název nakladatele

EEICT confrence, Brno university of technology

Místo vydání

Brno, Czech Republic

Místo konání akce

Brno

Datum konání akce

23. 4. 2024

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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