Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26220%2F24%3APU151868" target="_blank" >RIV/00216305:26220/24:PU151868 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1109/TSP63128.2024.10605914" target="_blank" >https://doi.org/10.1109/TSP63128.2024.10605914</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/TSP63128.2024.10605914" target="_blank" >10.1109/TSP63128.2024.10605914</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication

Popis výsledku v původním jazyce

Hypokinetic dysarthria (HD), prevalent in Parkin-son's disease (PD), is characterized by reduced motor movement, leading to speech and voice impairments. The effectiveness of dopamine therapy varies, and symptoms may change over time. To explore the HD in patients on medication, we conducted hierarchical clustering to categorize 83 PD patients using the acoustic features extracted from recorded text reading, sustained phonation, and diadochokinetic task. We then compared these clusters to a group of 44 healthy controls. Regardless of the medication dosage and PD duration, patients displayed three distinct speech profiles: articulatory; respiratory-prosodic; and another more complex/severe regarding the number of HD do-mains affected. The newly identified profiles exhibit distinctions from previously defined speech subtypes in de novo PD patients. No differences in clinical scores were observed among the newly identified profiles, suggesting uniformity in clinical presentation despite distinct speech characteristics.

Název v anglickém jazyce

Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication

Popis výsledku anglicky

Hypokinetic dysarthria (HD), prevalent in Parkin-son's disease (PD), is characterized by reduced motor movement, leading to speech and voice impairments. The effectiveness of dopamine therapy varies, and symptoms may change over time. To explore the HD in patients on medication, we conducted hierarchical clustering to categorize 83 PD patients using the acoustic features extracted from recorded text reading, sustained phonation, and diadochokinetic task. We then compared these clusters to a group of 44 healthy controls. Regardless of the medication dosage and PD duration, patients displayed three distinct speech profiles: articulatory; respiratory-prosodic; and another more complex/severe regarding the number of HD do-mains affected. The newly identified profiles exhibit distinctions from previously defined speech subtypes in de novo PD patients. No differences in clinical scores were observed among the newly identified profiles, suggesting uniformity in clinical presentation despite distinct speech characteristics.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Projekt

<a href="/cs/project/LX22NPO5107" target="_blank" >LX22NPO5107: Národní ústav pro neurologický výzkum</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

2024 47th International Conference on Telecommunications and Signal Processing (TSP)

ISBN

979-8-3503-6559-7

ISSN

—

e-ISSN

—

Počet stran výsledku

4

Strana od-do

270-273

Název nakladatele

IEEE

Místo vydání

neuveden

Místo konání akce

Prague

Datum konání akce

10. 7. 2024

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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