Syntéza a charakterizace biokompatibilních hydrogelů

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F05%3APU52533" target="_blank" >RIV/00216305:26310/05:PU52533 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Synthesis and characterization of biocompatible hydrogels

Popis výsledku v původním jazyce

The proposed project is focused on the synthesis, characterization and degradation kinetic study of well-defined multifunctional biocompatible and biodegradable polymer materials with controlled life-time additionally modified by renewable raw materials.These amphiphilic copolymers are based on the biodegradable macromonomers of hydrophilic poly(ethylene glycol) (PEG) with hydrophobic copolymer of lactic and glycolic acid (PLA/PGA), which are functionalized by itaconic acid. By changing the molecular weight and molar ratio of these compounds, amphiphilic character of resulted PEG-co-PLA/PGA macromonomers as well as the functional groups separation and, moreover, the kinetic of degradation is affected. Well-defined multifunctional macromonomers can b echemically or physically cross-linked in order to make 3D-polymer network Suggested materials might be further modified by an active chemical compounds to become candidates for a broad range of applications such as biomedical (e.g. inject

Název v anglickém jazyce

Synthesis and characterization of biocompatible hydrogels

Popis výsledku anglicky

The proposed project is focused on the synthesis, characterization and degradation kinetic study of well-defined multifunctional biocompatible and biodegradable polymer materials with controlled life-time additionally modified by renewable raw materials.These amphiphilic copolymers are based on the biodegradable macromonomers of hydrophilic poly(ethylene glycol) (PEG) with hydrophobic copolymer of lactic and glycolic acid (PLA/PGA), which are functionalized by itaconic acid. By changing the molecular weight and molar ratio of these compounds, amphiphilic character of resulted PEG-co-PLA/PGA macromonomers as well as the functional groups separation and, moreover, the kinetic of degradation is affected. Well-defined multifunctional macromonomers can b echemically or physically cross-linked in order to make 3D-polymer network Suggested materials might be further modified by an active chemical compounds to become candidates for a broad range of applications such as biomedical (e.g. inject

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

—

Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chemické listy (IF = 0.348)

ISSN

0009-2770

e-ISSN

—

Svazek periodika

99 (S)

Číslo periodika v rámci svazku

Symposia

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

2

Strana od-do

"s491"

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—