Application of real-time PCR for evaluation of magnetic nanoparticles in molecular diagnostics

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F11%3APU93110" target="_blank" >RIV/00216305:26310/11:PU93110 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Application of real-time PCR for evaluation of magnetic nanoparticles in molecular diagnostics

Popis výsledku v původním jazyce

In vitro amplification of nucleic acids using the polymerase chain reaction (PCR) has become a powerful diagnostic tool for the analysis of microorganisms. However, the sensitivity of PCR may be reduced when complex biological samples are studied, sincevarious extracellular PCR inhibitors may be present. The problem can be resolved by means of various DNA isolation and purification methods. Magnetic particles can be successfully used for the isolation of DNA from various samples containing PCR inhibitors. Research has been focused on the development of innovative magnetic nanoparticles.

Název v anglickém jazyce

Application of real-time PCR for evaluation of magnetic nanoparticles in molecular diagnostics

Popis výsledku anglicky

In vitro amplification of nucleic acids using the polymerase chain reaction (PCR) has become a powerful diagnostic tool for the analysis of microorganisms. However, the sensitivity of PCR may be reduced when complex biological samples are studied, sincevarious extracellular PCR inhibitors may be present. The problem can be resolved by means of various DNA isolation and purification methods. Magnetic particles can be successfully used for the isolation of DNA from various samples containing PCR inhibitors. Research has been focused on the development of innovative magnetic nanoparticles.

Druh

O - Ostatní výsledky

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů