Colloid Properties of Ultrasound Contrast Agents

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F13%3APU107860" target="_blank" >RIV/00216305:26310/13:PU107860 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Colloid Properties of Ultrasound Contrast Agents

Popis výsledku v původním jazyce

Microbubbles are used in biomedical field as diagnostic agents in combination with ultrasound. This imaging technique has also been proposed for drug or gene delivery to targeted regions. The aim of our study was to identify the potential of ultrasound agent SonoVue(R) for drug delivery. The properties of SonoVue(R) were investigated by dynamic light scattering method, centrifugal dispersion analysis and fluorescence spectroscopy measurement. Ability of incorporation of drug was studied with doxorubicinhydrochloride and hydrophobic fluorescent probe. We present results of a pilot study to determine colloid properties of SonoVue(R) microbubble suspension. The results will be used in subsequent experiments and for design a new drug delivery system.

Název v anglickém jazyce

Colloid Properties of Ultrasound Contrast Agents

Popis výsledku anglicky

Microbubbles are used in biomedical field as diagnostic agents in combination with ultrasound. This imaging technique has also been proposed for drug or gene delivery to targeted regions. The aim of our study was to identify the potential of ultrasound agent SonoVue(R) for drug delivery. The properties of SonoVue(R) were investigated by dynamic light scattering method, centrifugal dispersion analysis and fluorescence spectroscopy measurement. Ability of incorporation of drug was studied with doxorubicinhydrochloride and hydrophobic fluorescent probe. We present results of a pilot study to determine colloid properties of SonoVue(R) microbubble suspension. The results will be used in subsequent experiments and for design a new drug delivery system.

Druh

O - Ostatní výsledky

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/ED0012%2F01%2F01" target="_blank" >ED0012/01/01: Centra materiálového výzkumu na FCH VUT v Brně</a><br>

Návaznosti

O - Projekt operacniho programu

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů