Colloid Properties of Phospholipids Aggregates

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F14%3APU111198" target="_blank" >RIV/00216305:26310/14:PU111198 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Colloid Properties of Phospholipids Aggregates

Popis výsledku v původním jazyce

Microbubbles are used as contrast agents in combination with ultrasound mostly for cardiovascular imaging or the assessment of perfusion of various organs and tumors. The aim of our study was to evaluate ability of solubilization and formation process ofmicrobubble SonoVue phospholipid liposomes and surfactant micelles as basis for development of new contrast agent for drug delivery applications. Ability of solubilization was study using the UV-VIS spectroscopy and solubilizing capacity was determinedusing hydrophobic solutes because of obtaining a model system of solubilized drugs or vitamins which are also hydrophobic. Microbubble and liposomes formation process was investigated using surface tension measurements, specifically maximum bubble pressure method.

Název v anglickém jazyce

Colloid Properties of Phospholipids Aggregates

Popis výsledku anglicky

Microbubbles are used as contrast agents in combination with ultrasound mostly for cardiovascular imaging or the assessment of perfusion of various organs and tumors. The aim of our study was to evaluate ability of solubilization and formation process ofmicrobubble SonoVue phospholipid liposomes and surfactant micelles as basis for development of new contrast agent for drug delivery applications. Ability of solubilization was study using the UV-VIS spectroscopy and solubilizing capacity was determinedusing hydrophobic solutes because of obtaining a model system of solubilized drugs or vitamins which are also hydrophobic. Microbubble and liposomes formation process was investigated using surface tension measurements, specifically maximum bubble pressure method.

Druh

O - Ostatní výsledky

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/LO1211" target="_blank" >LO1211: Centrum materiálového výzkumu na FCH VUT v Brně - udržitelnost a rozvoj</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů