Using Candida glabrata for screening antifungal activity of plant extracts

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F18%3APU128530" target="_blank" >RIV/00216305:26310/18:PU128530 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Using Candida glabrata for screening antifungal activity of plant extracts

Popis výsledku v původním jazyce

This work aims at preservation of chosen plant extract from clove, garlic, ginger and turmeric into phospholipid nanoparticles in order to prolong their activity and stability to get better antifungal effect. Extracted antimicrobial compounds were characterized and packed into liposomes. These particles were characterized base on their encapsulation efficiency by spectrophotometry. Particle size and size distribution were observed by dynamic light scattering and stability in solution by determining zeta-potential. All of the prepared samples showed high activity against Candida glabrata in comparison with control. Encapsulation of active compounds from plants into liposomes can be an interesting way how to cure mycotic infections and can be potentially used as medical components or as preservants in cosmetics and food industry.

Název v anglickém jazyce

Using Candida glabrata for screening antifungal activity of plant extracts

Popis výsledku anglicky

This work aims at preservation of chosen plant extract from clove, garlic, ginger and turmeric into phospholipid nanoparticles in order to prolong their activity and stability to get better antifungal effect. Extracted antimicrobial compounds were characterized and packed into liposomes. These particles were characterized base on their encapsulation efficiency by spectrophotometry. Particle size and size distribution were observed by dynamic light scattering and stability in solution by determining zeta-potential. All of the prepared samples showed high activity against Candida glabrata in comparison with control. Encapsulation of active compounds from plants into liposomes can be an interesting way how to cure mycotic infections and can be potentially used as medical components or as preservants in cosmetics and food industry.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/LO1211" target="_blank" >LO1211: Centrum materiálového výzkumu na FCH VUT v Brně - udržitelnost a rozvoj</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů