Dried Blood Spot Self-Sampling with Automated Capillary Electrophoresis Processing for Clinical Analysis
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU140137" target="_blank" >RIV/00216305:26310/21:PU140137 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/68081715:_____/21:00539864 RIV/00216305:26310/21:PU147694
Výsledek na webu
<a href="https://www.scopus.com/record/display.uri?eid=2-s2.0-85100255896&origin=resultslist&sort=plf-f&src=s&st1=&st2=&sid=9347a1bcfae9ce08783f1dc8544c7df6&sot=b&sdt=b&sl=21&s=AUTHOR-NAME%28Rysava+L%29&relpos=2&citeCnt=0&searchTerm=" target="_blank" >https://www.scopus.com/record/display.uri?eid=2-s2.0-85100255896&origin=resultslist&sort=plf-f&src=s&st1=&st2=&sid=9347a1bcfae9ce08783f1dc8544c7df6&sot=b&sdt=b&sl=21&s=AUTHOR-NAME%28Rysava+L%29&relpos=2&citeCnt=0&searchTerm=</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/anie.202012997" target="_blank" >10.1002/anie.202012997</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Dried Blood Spot Self-Sampling with Automated Capillary Electrophoresis Processing for Clinical Analysis
Popis výsledku v původním jazyce
A simple and convenient concept of blood sampling followed by a fully automated analysis is presented. A disposable sampling kit is used for accurate self-sampling of capillary blood from a finger prick. A high-throughput blood sampling is thus enabled, which is essential in many clinical assays and considerably improves life quality and comfort of involved subjects. The collected blood samples are mailed to a laboratory for a fully automated dried blood spot (DBS) processing and analysis, which are performed with a commercial capillary electrophoresis instrument. Quantitative results are obtained within 20 min from the DBS delivery to the laboratory. The presented concept is exemplified by the determination of warfarin blood concentrations and demonstrates excellent analytical performance. Moreover, this concept is generally applicable to a wide range of endogenous and exogenous blood compounds and represents a novel and attractive analytical tool for personalized health monitoring.
Název v anglickém jazyce
Dried Blood Spot Self-Sampling with Automated Capillary Electrophoresis Processing for Clinical Analysis
Popis výsledku anglicky
A simple and convenient concept of blood sampling followed by a fully automated analysis is presented. A disposable sampling kit is used for accurate self-sampling of capillary blood from a finger prick. A high-throughput blood sampling is thus enabled, which is essential in many clinical assays and considerably improves life quality and comfort of involved subjects. The collected blood samples are mailed to a laboratory for a fully automated dried blood spot (DBS) processing and analysis, which are performed with a commercial capillary electrophoresis instrument. Quantitative results are obtained within 20 min from the DBS delivery to the laboratory. The presented concept is exemplified by the determination of warfarin blood concentrations and demonstrates excellent analytical performance. Moreover, this concept is generally applicable to a wide range of endogenous and exogenous blood compounds and represents a novel and attractive analytical tool for personalized health monitoring.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10406 - Analytical chemistry
Návaznosti výsledku
Projekt
<a href="/cs/project/GA18-13135S" target="_blank" >GA18-13135S: Využití kapilární elektroforézy při analýze suchých krevních skvrn</a><br>
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2021
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
ISSN
1433-7851
e-ISSN
1521-3773
Svazek periodika
60
Číslo periodika v rámci svazku
11
Stát vydavatele periodika
DE - Spolková republika Německo
Počet stran výsledku
9
Strana od-do
6068-3075
Kód UT WoS článku
000613441700001
EID výsledku v databázi Scopus
—