Structural and Mechanical Analyses of Hydrogel Systems Modified by Lecithin Nanodomains

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F21%3APU141893" target="_blank" >RIV/00216305:26310/21:PU141893 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Structural and Mechanical Analyses of Hydrogel Systems Modified by Lecithin Nanodomains

Popis výsledku v původním jazyce

Design of the hydrogels with the tunable properties capable to imitate native extracellular matrix (ECM) is widely discussed topic in recent years. With respect to faithful imitation of ECM, this proposed study mostly utilizes biocompatible and biodegradable materials with ability to form crosslinked 3D networks (hydrogels) with further potential use as barrier materials, drug carrier in regenerative medicine, tissue engineering, etc. The inner structure (related to viscoelastic and transport properties) of the basic 3D matrix material were modified by phospholipid lecithin, which in water-based solutions forms organized nanodomain structures and consequently affects the final structural properties of the prepared hydrogels. These structural modifications then consequently lead to distinct mechanical properties. Hydrogel systems, physically, chemically, and ionically crosslinked, were subjected to the structural characterization in the dried form of xerogel using direct visualization technique (scann

Název v anglickém jazyce

Structural and Mechanical Analyses of Hydrogel Systems Modified by Lecithin Nanodomains

Popis výsledku anglicky

Design of the hydrogels with the tunable properties capable to imitate native extracellular matrix (ECM) is widely discussed topic in recent years. With respect to faithful imitation of ECM, this proposed study mostly utilizes biocompatible and biodegradable materials with ability to form crosslinked 3D networks (hydrogels) with further potential use as barrier materials, drug carrier in regenerative medicine, tissue engineering, etc. The inner structure (related to viscoelastic and transport properties) of the basic 3D matrix material were modified by phospholipid lecithin, which in water-based solutions forms organized nanodomain structures and consequently affects the final structural properties of the prepared hydrogels. These structural modifications then consequently lead to distinct mechanical properties. Hydrogel systems, physically, chemically, and ionically crosslinked, were subjected to the structural characterization in the dried form of xerogel using direct visualization technique (scann

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10403 - Physical chemistry

Projekt

<a href="/cs/project/EF19_073%2F0016948" target="_blank" >EF19_073/0016948: Kvalitní interní granty VUT</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů