Fluorescence study of some structural and compositional effects on the aggregation of hydrophobized hyaluronan

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F22%3APU146919" target="_blank" >RIV/00216305:26310/22:PU146919 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S2215038222000942?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2215038222000942?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.colcom.2022.100677" target="_blank" >10.1016/j.colcom.2022.100677</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Fluorescence study of some structural and compositional effects on the aggregation of hydrophobized hyaluronan

Popis výsledku v původním jazyce

The aggregation behavior of four samples of hydrophobically modified hyaluronan was examined in water and in 0.15 M NaCl. The samples differed in the length of their hydrocarbon modifying chains, degree of substitution, or hyaluronan molecular weight. The critical aggregation concentration was determined by fluorescence spec-troscopy using pyrene as a probe. Aggregation was observed even with hyaluronan modified by a short alkyl chain (C6). The critical aggregation concentration decreased with increasing alkyl chain length and with increasing hyaluronan molecular weight at a comparable degree of substitution. Aggregation was detected over a rather broad concentration interval, indicating a progressive formation of aggregates. Two populations of ag-gregates were detected for the oleyl substitution. The addition of NaCl had only minor effect on the critical aggregation concentration.

Název v anglickém jazyce

Fluorescence study of some structural and compositional effects on the aggregation of hydrophobized hyaluronan

Popis výsledku anglicky

The aggregation behavior of four samples of hydrophobically modified hyaluronan was examined in water and in 0.15 M NaCl. The samples differed in the length of their hydrocarbon modifying chains, degree of substitution, or hyaluronan molecular weight. The critical aggregation concentration was determined by fluorescence spec-troscopy using pyrene as a probe. Aggregation was observed even with hyaluronan modified by a short alkyl chain (C6). The critical aggregation concentration decreased with increasing alkyl chain length and with increasing hyaluronan molecular weight at a comparable degree of substitution. Aggregation was detected over a rather broad concentration interval, indicating a progressive formation of aggregates. Two populations of ag-gregates were detected for the oleyl substitution. The addition of NaCl had only minor effect on the critical aggregation concentration.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10403 - Physical chemistry

Projekt

<a href="/cs/project/GC19-14024J" target="_blank" >GC19-14024J: Hyaluronan-kataniontové vezikulární komplexy - interakce, struktura, fyzikální vlastnosti a stabilita</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Colloids and Interface Science Communications

ISSN

2215-0382

e-ISSN

—

Svazek periodika

51

Číslo periodika v rámci svazku

100667

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

1-6

Kód UT WoS článku

000899010900005

EID výsledku v databázi Scopus

2-s2.0-85141807732