Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26310%2F26%3A0199015" target="_blank" >RIV/00216305:26310/26:0199015 - isvavai.cz</a>
Výsledek na webu
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DOI - Digital Object Identifier
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Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles
Popis výsledku v původním jazyce
Ion pair amphiphile, prepared from mixed cationic/anionic surfactants, has a pseudodouble-chain structure and can be used as a raw material to form a vesicular structure, or catanionic vesicle, in aqueous phase. It has been demonstrated that catanionic vesicles could be fabricated from the ion pair amphiphile hexadecyltrimethylammonium-dodecylsulfate (HTMA:DS) by using a forced formation process with the addition of double-chain cationic surfactants, dialkyldimethylammonium bromide (DXDAB), and the physical stability of the HTMA:DS/DXDAB catanionic vesicles could be further improved in the presence of cholesterol. Through the analysis of bilayer fluidity and solvation, as well as the data integration of different analysis methods, combined with molecular dynamics simulations, the complex effects of the added cholesterol on the molecular arrangement and interaction in the bilayer structures of the HTMA:DS/DXDAB catanionic vesicles were elucidated.
Název v anglickém jazyce
Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles
Popis výsledku anglicky
Ion pair amphiphile, prepared from mixed cationic/anionic surfactants, has a pseudodouble-chain structure and can be used as a raw material to form a vesicular structure, or catanionic vesicle, in aqueous phase. It has been demonstrated that catanionic vesicles could be fabricated from the ion pair amphiphile hexadecyltrimethylammonium-dodecylsulfate (HTMA:DS) by using a forced formation process with the addition of double-chain cationic surfactants, dialkyldimethylammonium bromide (DXDAB), and the physical stability of the HTMA:DS/DXDAB catanionic vesicles could be further improved in the presence of cholesterol. Through the analysis of bilayer fluidity and solvation, as well as the data integration of different analysis methods, combined with molecular dynamics simulations, the complex effects of the added cholesterol on the molecular arrangement and interaction in the bilayer structures of the HTMA:DS/DXDAB catanionic vesicles were elucidated.
Klasifikace
Druh
C - Kapitola v odborné knize
CEP obor
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OECD FORD obor
10403 - Physical chemistry
Návaznosti výsledku
Projekt
<a href="/cs/project/GC19-14024J" target="_blank" >GC19-14024J: Hyaluronan-kataniontové vezikulární komplexy - interakce, struktura, fyzikální vlastnosti a stabilita</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2025
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název knihy nebo sborníku
Physical Chemistry in Action, Colloids and Interfacial Dynamics
ISBN
9789819667277
Počet stran výsledku
20
Strana od-do
247-266
Počet stran knihy
368
Název nakladatele
Springer Nature Singapore
Místo vydání
Singapore
Kód UT WoS kapitoly
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