Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00843989%3A_____%2F23%3AE0110426" target="_blank" >RIV/00843989:_____/23:E0110426 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/23:00133659 RIV/61989100:27350/23:10252822 RIV/61989100:27360/23:10252822 RIV/61989100:27640/23:10252822

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1382668923002247?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1382668923002247?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.etap.2023.104282" target="_blank" >10.1016/j.etap.2023.104282</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study

Popis výsledku v původním jazyce

The presence of particles fixed in tissue samples due to implant degradation or disintegration plays an important role in post-operative complications. The ability to determine the size, shape, chemical composition and, above all, the number of these particles can be used in many areas of medicine. This study presents a novel, simple metal-based particle detection method using scanning electron microscopy with energy dispersive spectrometer (SEM-EDS). The presence of metal particles in biopsy specimens from long bone nail-fixated implants (10 patients with titanium steel nails and 10 patients with stainless steel nails) was studied. The samples were analysed using automated area analysis based on image binarization and brightness to 255 grayscale. The results were supplemented with histological data and statistically analysed. The method based on the software used was found to be accurate and easy to use and, thus, appears to be very suitable for particle detection in similar samples.

Název v anglickém jazyce

Simple method for quantification of metal-based particles in biopsy samples of patients with long bone implants - Pilot study

Popis výsledku anglicky

The presence of particles fixed in tissue samples due to implant degradation or disintegration plays an important role in post-operative complications. The ability to determine the size, shape, chemical composition and, above all, the number of these particles can be used in many areas of medicine. This study presents a novel, simple metal-based particle detection method using scanning electron microscopy with energy dispersive spectrometer (SEM-EDS). The presence of metal particles in biopsy specimens from long bone nail-fixated implants (10 patients with titanium steel nails and 10 patients with stainless steel nails) was studied. The samples were analysed using automated area analysis based on image binarization and brightness to 255 grayscale. The results were supplemented with histological data and statistically analysed. The method based on the software used was found to be accurate and easy to use and, thus, appears to be very suitable for particle detection in similar samples.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Environmental toxicology and pharmacology

ISSN

1382-6689

e-ISSN

1872-7077

Svazek periodika

103

Číslo periodika v rámci svazku

article 104282

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

1-7

Kód UT WoS článku

001097249400001

EID výsledku v databázi Scopus

2-s2.0-85172249185