Functional analysis of R2R3 transcription factor HIMyb8 from hop (Humulus lupulus L.) and its role in lupulin-specific flavonoid biosynthesis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F14864347%3A_____%2F17%3AN0000069" target="_blank" >RIV/14864347:_____/17:N0000069 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.lfl.bayern.de/ipz/hopfen/024299/" target="_blank" >http://www.lfl.bayern.de/ipz/hopfen/024299/</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Functional analysis of R2R3 transcription factor HIMyb8 from hop (Humulus lupulus L.) and its role in lupulin-specific flavonoid biosynthesis

Popis výsledku v původním jazyce

KOCÁBEK, Tomáš, Jaroslav MATOUŠEK, Ajay Kumar MISHRA, A. LOMNICKÁ, Mudra KHARE, Josef PATZAK and G. S. DURAISAMY. Functional analysis of R2R3 transcription factor HIMyb8 from hop (Humulus lupulus L.) and its role in lupulin-specific flavonoid biosynthesis. In: F. WEIHRAUCH, ed. Proceedings of the Scientific-Technical Commission 25 – 29 June 2017, St. Stefan am Walde, Austria. Wolnzach: Scientific-Technical Commission of the International Hop Growers´ Convention, 2017, p. 84. ISSN 2512-3785. Hop lupulin glands consist of several biologically active components, including prenylflavonoids, with beneficial effects for human health. Biosynthesis of the flavonoids is controlled by the transcription factors (TFs) belonging to the different families such as WD40 repeat (W), bHLH (B), MYB (M), WRKY or bZIP as well as by exogenous factors. A combinatorial action of lupulin gland specific transcription factors in the regulation of the HlChs_H1 gene has already been demonstrated (MATOUŠEK et al. 2012). The early steps of flavonoid biosynthesis are driven independently by Myb TFs without the involvement of MBW complex. In order to gain in-depth knowledge of regulatory role of other unidentified TFs in flavonoid biosynthesis pathway in hop lupulin glands, we isolated and identified a new putative TF based on its significant similarity to MYB12 (At2G47460) of Arabidopsis thaliana (MEHRTENS et al. 2005).

Název v anglickém jazyce

Functional analysis of R2R3 transcription factor HIMyb8 from hop (Humulus lupulus L.) and its role in lupulin-specific flavonoid biosynthesis

Popis výsledku anglicky

KOCÁBEK, Tomáš, Jaroslav MATOUŠEK, Ajay Kumar MISHRA, A. LOMNICKÁ, Mudra KHARE, Josef PATZAK and G. S. DURAISAMY. Functional analysis of R2R3 transcription factor HIMyb8 from hop (Humulus lupulus L.) and its role in lupulin-specific flavonoid biosynthesis. In: F. WEIHRAUCH, ed. Proceedings of the Scientific-Technical Commission 25 – 29 June 2017, St. Stefan am Walde, Austria. Wolnzach: Scientific-Technical Commission of the International Hop Growers´ Convention, 2017, p. 84. ISSN 2512-3785. Hop lupulin glands consist of several biologically active components, including prenylflavonoids, with beneficial effects for human health. Biosynthesis of the flavonoids is controlled by the transcription factors (TFs) belonging to the different families such as WD40 repeat (W), bHLH (B), MYB (M), WRKY or bZIP as well as by exogenous factors. A combinatorial action of lupulin gland specific transcription factors in the regulation of the HlChs_H1 gene has already been demonstrated (MATOUŠEK et al. 2012). The early steps of flavonoid biosynthesis are driven independently by Myb TFs without the involvement of MBW complex. In order to gain in-depth knowledge of regulatory role of other unidentified TFs in flavonoid biosynthesis pathway in hop lupulin glands, we isolated and identified a new putative TF based on its significant similarity to MYB12 (At2G47460) of Arabidopsis thaliana (MEHRTENS et al. 2005).

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

40401 - Agricultural biotechnology and food biotechnology

Projekt

<a href="/cs/project/GA13-03037S" target="_blank" >GA13-03037S: Kombinační regulace a regulační síť transkripčních faktorů účastnících se biosyntézy ozdravných prenylflavonoidů chmelu (Humulus lupulus L.).</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů