Uniaxial tensile testing device for measuring mechanical properties of biological tissue with stress-relaxation test under a confocal microscope

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13420%2F18%3A43894150" target="_blank" >RIV/44555601:13420/18:43894150 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11510/18:10382591

Výsledek na webu

<a href="http://dx.doi.org/10.21062/ujep/180.2018/a/1213-2489/MT/18/5/866" target="_blank" >http://dx.doi.org/10.21062/ujep/180.2018/a/1213-2489/MT/18/5/866</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.21062/ujep/180.2018/a/1213-2489/MT/18/5/866" target="_blank" >10.21062/ujep/180.2018/a/1213-2489/MT/18/5/866</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Uniaxial tensile testing device for measuring mechanical properties of biological tissue with stress-relaxation test under a confocal microscope

Popis výsledku v původním jazyce

Biological soft tissue is a non-linear and viscoelastic material and its mechanical properties can greatly affect qual-ity of life. Many external mechanical factors can alter the tissue, for example the tissue of talipes equinovarus congenitus, also known as clubfoot, which is the most frequent congenital deformity affecting lower extremities with pathological changes of connective tissue. In clubfoot, the presence of disc-like mass of fibrous tissue, resembling intervertebral disc tissue, is described to be between the medial malleolus and the medial side of the navicular bone. The clubfoot tissue is often referred to be stiffer or rigid by clinicians, or it is referred to as contracted and less contracted tissue, however relevant evidence about mechanical properties is missing. Therefore, the description &quot;disc-like&quot; is informing only about relative mechanical properties of clubfoot tissue. We aim to prepare methodical approach to quantify mechanical properties of biological tissue with uniaxial tensile stress-relaxation test, in order to help clinicians and scientist to identify precisely the mechanical properties of normal and pathological tissue and their structural behaviour during mechanical testing. In this study, we test and tune the uniaxial tensile stress-relaxation test on biological tissue with high content of connective tissue such as collagen. The model tissue is porcine pericardium. The tissue has clear collagen fibres aligning parallel to the force applied. Modulus of elasticity measured here is comparable to other studies.

Název v anglickém jazyce

Uniaxial tensile testing device for measuring mechanical properties of biological tissue with stress-relaxation test under a confocal microscope

Popis výsledku anglicky

Biological soft tissue is a non-linear and viscoelastic material and its mechanical properties can greatly affect qual-ity of life. Many external mechanical factors can alter the tissue, for example the tissue of talipes equinovarus congenitus, also known as clubfoot, which is the most frequent congenital deformity affecting lower extremities with pathological changes of connective tissue. In clubfoot, the presence of disc-like mass of fibrous tissue, resembling intervertebral disc tissue, is described to be between the medial malleolus and the medial side of the navicular bone. The clubfoot tissue is often referred to be stiffer or rigid by clinicians, or it is referred to as contracted and less contracted tissue, however relevant evidence about mechanical properties is missing. Therefore, the description &quot;disc-like&quot; is informing only about relative mechanical properties of clubfoot tissue. We aim to prepare methodical approach to quantify mechanical properties of biological tissue with uniaxial tensile stress-relaxation test, in order to help clinicians and scientist to identify precisely the mechanical properties of normal and pathological tissue and their structural behaviour during mechanical testing. In this study, we test and tune the uniaxial tensile stress-relaxation test on biological tissue with high content of connective tissue such as collagen. The model tissue is porcine pericardium. The tissue has clear collagen fibres aligning parallel to the force applied. Modulus of elasticity measured here is comparable to other studies.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

20301 - Mechanical engineering

Projekt

<a href="/cs/project/LM2015062" target="_blank" >LM2015062: Národní infrastruktura pro biologické a medicínské zobrazování</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Manufacturing Technology

ISSN

1213-2489

e-ISSN

—

Svazek periodika

18

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

866-872

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85058047305