Simulation of the effect of N2O on DNA damage by ionizing radiation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13440%2F24%3A43899091" target="_blank" >RIV/44555601:13440/24:43899091 - isvavai.cz</a>

Výsledek na webu

<a href="https://wseas.com/journals/msa/2024/a065108-241.pdf" target="_blank" >https://wseas.com/journals/msa/2024/a065108-241.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.37394/232023.2024.4.3" target="_blank" >10.37394/232023.2024.4.3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Simulation of the effect of N2O on DNA damage by ionizing radiation

Popis výsledku v původním jazyce

Damage to the DNA molecule by ionizing radiation can be influenced by the presence ofcertain chemicals in the cell during irradiation. These substances can be both radioprotective andradiosensitive. In this paper, we will discuss the effect of N2O, widely used in medicine, on the chemicalstage of the radiobiological mechanism. N2O in the cell during irradiation with ionizing radiation results? toin more significant damage to the DNA molecule because N2O reacts with hydrated electrons ??? form aggressive OH radicals. A mathematical simulation model developed using hybrid Petri nets isused to analyze this dynamic process. Hybrid Petri nets allow us to quickly create a mathematicalsimulation model and explore the system under study to obtain detailed information for practicalapplications.

Název v anglickém jazyce

Simulation of the effect of N2O on DNA damage by ionizing radiation

Popis výsledku anglicky

Damage to the DNA molecule by ionizing radiation can be influenced by the presence ofcertain chemicals in the cell during irradiation. These substances can be both radioprotective andradiosensitive. In this paper, we will discuss the effect of N2O, widely used in medicine, on the chemicalstage of the radiobiological mechanism. N2O in the cell during irradiation with ionizing radiation results? toin more significant damage to the DNA molecule because N2O reacts with hydrated electrons ??? form aggressive OH radicals. A mathematical simulation model developed using hybrid Petri nets isused to analyze this dynamic process. Hybrid Petri nets allow us to quickly create a mathematicalsimulation model and explore the system under study to obtain detailed information for practicalapplications.

Druh

J_ost - Ostatní články v recenzovaných periodicích

CEP obor

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OECD FORD obor

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Molecular Sciences and Applications

ISSN

2944-9138

e-ISSN

2732-9992

Svazek periodika

2024

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

GR - Řecká republika

Počet stran výsledku

15

Strana od-do

19-33

Kód UT WoS článku

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EID výsledku v databázi Scopus

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