Simulation of the influence of N2O on the chemical stage of water radiolysis
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13440%2F22%3A43897359" target="_blank" >RIV/44555601:13440/22:43897359 - isvavai.cz</a>
Výsledek na webu
<a href="https://scholar.google.cz/scholar?q=Simulation+of+the+influence+of+N2O+on+the+chemical+stage+of+water+radiolysis&hl=cs&as_sdt=0&as_vis=1&oi=scholart" target="_blank" >https://scholar.google.cz/scholar?q=Simulation+of+the+influence+of+N2O+on+the+chemical+stage+of+water+radiolysis&hl=cs&as_sdt=0&as_vis=1&oi=scholart</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.37394/23208.2022.19.7" target="_blank" >10.37394/23208.2022.19.7</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Simulation of the influence of N2O on the chemical stage of water radiolysis
Popis výsledku v původním jazyce
Abstract: - The absorption of ionizing radiation causes the radiolysis of water to form aggressive radicals. Water radiolysis plays an essential role in radiotherapy, radio sterilization, food irradiation, and wastewater irradiation because living cells consist mainly of water. Radical clusters arise immediately after irradiating water with ionizing radiation, and aggressive radicals damage living cells. These damages are caused mainly by SSB and DSB formation on DNA molecules. The mathematical simulation model, created with the help of Continuous Petri nets, is very suitable to study the dynamics of the chemical stage of water radiolysis. This mathematical simulation model, which includes the influence of oxygen on the chemical stage of radiobiological mechanism, was created in our previous work. This paper is extended to include the influence of N2O. The presence of N2O during irradiation of water plays a vital role because it increases OH radicals, which are mainly responsible for DNA damage. The mathematical model enables us to simulate the dynamics of the chemical reactions and the diffusion of radical clusters during chemical stage of water radiolysis.
Název v anglickém jazyce
Simulation of the influence of N2O on the chemical stage of water radiolysis
Popis výsledku anglicky
Abstract: - The absorption of ionizing radiation causes the radiolysis of water to form aggressive radicals. Water radiolysis plays an essential role in radiotherapy, radio sterilization, food irradiation, and wastewater irradiation because living cells consist mainly of water. Radical clusters arise immediately after irradiating water with ionizing radiation, and aggressive radicals damage living cells. These damages are caused mainly by SSB and DSB formation on DNA molecules. The mathematical simulation model, created with the help of Continuous Petri nets, is very suitable to study the dynamics of the chemical stage of water radiolysis. This mathematical simulation model, which includes the influence of oxygen on the chemical stage of radiobiological mechanism, was created in our previous work. This paper is extended to include the influence of N2O. The presence of N2O during irradiation of water plays a vital role because it increases OH radicals, which are mainly responsible for DNA damage. The mathematical model enables us to simulate the dynamics of the chemical reactions and the diffusion of radical clusters during chemical stage of water radiolysis.
Klasifikace
Druh
J<sub>SC</sub> - Článek v periodiku v databázi SCOPUS
CEP obor
—
OECD FORD obor
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Návaznosti výsledku
Projekt
—
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2022
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
WSEAS Transactions on Biology and Biomedicine
ISSN
1109-9518
e-ISSN
2224-2902
Svazek periodika
2022
Číslo periodika v rámci svazku
19
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
16
Strana od-do
47-62
Kód UT WoS článku
—
EID výsledku v databázi Scopus
2-s2.0-85176100928