DEVELOPMENT OF FIBROUS IMPLANT FOR THE TREATMENT OF GLAUCOMA

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24210%2F16%3A00003880" target="_blank" >RIV/46747885:24210/16:00003880 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/46747885:24410/16:00003880

Výsledek na webu

<a href="http://www.nanocon.eu" target="_blank" >http://www.nanocon.eu</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

DEVELOPMENT OF FIBROUS IMPLANT FOR THE TREATMENT OF GLAUCOMA

Popis výsledku v původním jazyce

This article deals with the development of fibrous non-biodegradable drainage device for the treatment of glaucoma disease. Currently produced implants are often associated with hypotony, undesired fibrosis, tissue damages around the implant and many others [1]. Nanofiber implant has great potential to alleviate or completely eliminate these problems. The main goal of this work was a creation of the drain for safety drainage of intraocular fluid from the patient eye to achieve a normal intraocular pressure. The small-diameter tubular implant (<1 mm) was developed by the use of the electrospinning technology. The structure was composed of two parts, by using special types of collectors. The outer part was formed of non-biodegradable material that is resistant to cell growth. The inner supporting part was formed of hydrophilic material which is also resistant to cell growth. This part prevents the compression of the outer material and a total blockage of the drain. The special structure supports the drainage of fluid. Material was subjected to morphological structures, liquid transport tests and in-vitro cell adhesion tests. First results show great potential in the use of the implant in treatment of glaucoma disease.

Název v anglickém jazyce

DEVELOPMENT OF FIBROUS IMPLANT FOR THE TREATMENT OF GLAUCOMA

Popis výsledku anglicky

This article deals with the development of fibrous non-biodegradable drainage device for the treatment of glaucoma disease. Currently produced implants are often associated with hypotony, undesired fibrosis, tissue damages around the implant and many others [1]. Nanofiber implant has great potential to alleviate or completely eliminate these problems. The main goal of this work was a creation of the drain for safety drainage of intraocular fluid from the patient eye to achieve a normal intraocular pressure. The small-diameter tubular implant (<1 mm) was developed by the use of the electrospinning technology. The structure was composed of two parts, by using special types of collectors. The outer part was formed of non-biodegradable material that is resistant to cell growth. The inner supporting part was formed of hydrophilic material which is also resistant to cell growth. This part prevents the compression of the outer material and a total blockage of the drain. The special structure supports the drainage of fluid. Material was subjected to morphological structures, liquid transport tests and in-vitro cell adhesion tests. First results show great potential in the use of the implant in treatment of glaucoma disease.

Druh

D - Stať ve sborníku

CEP obor

JJ - Ostatní materiály

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

NANOCON 2016 - Conference Proceedings, 8th International Conference on Nanomaterials - Research and Application

ISBN

9788087294710

ISSN

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e-ISSN

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Počet stran výsledku

6

Strana od-do

497-502

Název nakladatele

TANGER spol. s r.o.

Místo vydání

Ostrava

Místo konání akce

Brno

Datum konání akce

1. 1. 2016

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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