Composite fibrous glaucoma drainage implant

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24210%2F17%3A00004806" target="_blank" >RIV/46747885:24210/17:00004806 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/46747885:24410/17:00004806

Výsledek na webu

<a href="http://dx.doi.org/10.1088/1757-899X/254/6/062006" target="_blank" >http://dx.doi.org/10.1088/1757-899X/254/6/062006</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1088/1757-899X/254/6/062006" target="_blank" >10.1088/1757-899X/254/6/062006</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Composite fibrous glaucoma drainage implant

Popis výsledku v původním jazyce

Glaucoma is a frequent reason of loss vision. It is usually caused by increased intraocular pressure leading to damage of optic nerve head. This work deals with the development of fibrous structure suitable for glaucoma drainage implants (GDI). Commercially produced metallic glaucoma implants are very effective in lowering intraocular pressure. However, these implants may cause adverse events such as damage to adjacent tissue, fibrosis, hypotony or many others [1]. The aim of this study is to reduce undesirable properties of currently produced drains and improve their properties by creating of the composite fibrous drain for achieve a normal intraocular pressure. Two types of electrospinning technologies were used for the production of very small tubular implants. First type was focused for production of outer part of tubular drain and the second type of electrospinning method made the inner part of shape follows the connections of both parts. Complete implant had a special properties suitable for drainage of fluid. Morphological parameters, liquid transport tests and in-vitro cell adhesion tests were detected.

Název v anglickém jazyce

Composite fibrous glaucoma drainage implant

Popis výsledku anglicky

Glaucoma is a frequent reason of loss vision. It is usually caused by increased intraocular pressure leading to damage of optic nerve head. This work deals with the development of fibrous structure suitable for glaucoma drainage implants (GDI). Commercially produced metallic glaucoma implants are very effective in lowering intraocular pressure. However, these implants may cause adverse events such as damage to adjacent tissue, fibrosis, hypotony or many others [1]. The aim of this study is to reduce undesirable properties of currently produced drains and improve their properties by creating of the composite fibrous drain for achieve a normal intraocular pressure. Two types of electrospinning technologies were used for the production of very small tubular implants. First type was focused for production of outer part of tubular drain and the second type of electrospinning method made the inner part of shape follows the connections of both parts. Complete implant had a special properties suitable for drainage of fluid. Morphological parameters, liquid transport tests and in-vitro cell adhesion tests were detected.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

IOP Conference Series: Materials Science and Engineering

ISBN

—

ISSN

1757-8981

e-ISSN

—

Počet stran výsledku

6

Strana od-do

—

Název nakladatele

Institute of Physics Publishing (IOP Science)

Místo vydání

—

Místo konání akce

Corfu, Greece

Datum konání akce

1. 1. 2017

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000417214900055