Importance and necessity of the surface modification of nylon 6 films for future biomedical application

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24220%2F16%3A00004385" target="_blank" >RIV/46747885:24220/16:00004385 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/46747885:24510/16:00004385 RIV/46747885:24620/16:00004385

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Importance and necessity of the surface modification of nylon 6 films for future biomedical application

Popis výsledku v původním jazyce

Polyamide plays an important role in biomedical application such as suture material, coated textile against skin infection, wound dressing, catheters and bone tissue scaffolds. Surface modification of polyamide is very crucial factor to improve its performances by imparting desirable biomaterial properties. This report is focused on the efficient reduction of amide functional groups to secondary amine on Nylon 6 film surface with borane-tetrahydrofuran (BH3-THF) complex, followed by further alkylation. More precisely, we have studied the reaction of benzyl chloride (C6H5CH2Cl) in presence of potassium tert-butoxide (t-BuOK) on the modified Nylon 6 films. Thus, introduction of benzyl group to secondary amine of modified Nylon 6 has been accomplished. This type of transformation is expected to be generally applicable for functionalization of almost any polyamide. By using different alkylation reactions we will be able to tune the surface properties of polymers obtained for almost any applications. We also hope that polymers thus obtained will be biocompatible. The surface modifications were confirmed by both non-spectral methods and spectroscopic as well as microscopic analyses. Water contact angle (WCA) and free surface energy (FSE) measurements indicated the significant change in surface morphology that were established by X-ray photoelectron spectroscopy (XPS), Fourier-transform infrared spectroscopy (FT-IR), Raman spectroscopy and atomic force microscopy (AFM). We are firmly convinced of the future prospect for further surface modification of these functionalized nylon 6 films with high potential in the field of biomedical application.

Název v anglickém jazyce

Importance and necessity of the surface modification of nylon 6 films for future biomedical application

Popis výsledku anglicky

Polyamide plays an important role in biomedical application such as suture material, coated textile against skin infection, wound dressing, catheters and bone tissue scaffolds. Surface modification of polyamide is very crucial factor to improve its performances by imparting desirable biomaterial properties. This report is focused on the efficient reduction of amide functional groups to secondary amine on Nylon 6 film surface with borane-tetrahydrofuran (BH3-THF) complex, followed by further alkylation. More precisely, we have studied the reaction of benzyl chloride (C6H5CH2Cl) in presence of potassium tert-butoxide (t-BuOK) on the modified Nylon 6 films. Thus, introduction of benzyl group to secondary amine of modified Nylon 6 has been accomplished. This type of transformation is expected to be generally applicable for functionalization of almost any polyamide. By using different alkylation reactions we will be able to tune the surface properties of polymers obtained for almost any applications. We also hope that polymers thus obtained will be biocompatible. The surface modifications were confirmed by both non-spectral methods and spectroscopic as well as microscopic analyses. Water contact angle (WCA) and free surface energy (FSE) measurements indicated the significant change in surface morphology that were established by X-ray photoelectron spectroscopy (XPS), Fourier-transform infrared spectroscopy (FT-IR), Raman spectroscopy and atomic force microscopy (AFM). We are firmly convinced of the future prospect for further surface modification of these functionalized nylon 6 films with high potential in the field of biomedical application.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/LO1201" target="_blank" >LO1201: ROZVOJ ÚSTAVU PRO NANOMATERIÁLY, POKROČILÉ TECHNOLOGIE A INOVACE TECHNICKÉ UNIVERZITY V LIBERCI</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

NANOCON 2016 - Conference Proceedings, 8th International Conference on Nanomaterials - Research and Application

ISBN

978-80-87294-71-0

ISSN

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e-ISSN

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Počet stran výsledku

6

Strana od-do

663-668

Název nakladatele

TANGER LTD, KELTICKOVA 62, SLEZSKA, OSTRAVA 710 00, CZECH REPUBLIC

Místo vydání

Ostrava

Místo konání akce

Brno

Datum konání akce

1. 1. 2016

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000410656100115