A comparative study between chemically modified and copper nanoparticle immobilized Nylon 6 films to explore their efficiency in fighting against two types of pathogenic bacteria

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24220%2F20%3A00006855" target="_blank" >RIV/46747885:24220/20:00006855 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/46747885:24410/20:00006855 RIV/46747885:24620/20:00006855 RIV/46747885:24210/20:00006855

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0014305719318567?via=ihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0014305719318567?via=ihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.eurpolymj.2019.109392" target="_blank" >10.1016/j.eurpolymj.2019.109392</a>

Jazyk výsledku

angličtina

Název v původním jazyce

A comparative study between chemically modified and copper nanoparticle immobilized Nylon 6 films to explore their efficiency in fighting against two types of pathogenic bacteria

Popis výsledku v původním jazyce

Staphylococcus aureus adversely affect public health due to their colonization and subsequent formation of a biofilm on medical devices. Various functionalized polymers including polyamides are commonly used in the biomedical industry aiming to resist bacterial infection as well as to ensure cytocompatibility of the used materials. The present study is focused on the extension of our previous work that developed a new approach to immobilize mPEG on an amine-activated Nylon 6 surface. Herein, we compare functionalized samples of Nylon 6 together with samples additionally containing copper nanoparticles (Cu NPs, size 40–60 nm) physisorbed on a modified surface. Modified samples were analyzed via different techniques including water contact angle measurements, atomic force microscopy and scanning electron microscopy associated with energy dispersive Xray spectroscopy. The copper functionalized samples showed high antibacterial efficacy against Gram-positive Staphylococcus aureus and Gram-negative Pseudomonas aeruginosa. Moreover, most of the prepared samples were cytocompatible.

Název v anglickém jazyce

A comparative study between chemically modified and copper nanoparticle immobilized Nylon 6 films to explore their efficiency in fighting against two types of pathogenic bacteria

Popis výsledku anglicky

Staphylococcus aureus adversely affect public health due to their colonization and subsequent formation of a biofilm on medical devices. Various functionalized polymers including polyamides are commonly used in the biomedical industry aiming to resist bacterial infection as well as to ensure cytocompatibility of the used materials. The present study is focused on the extension of our previous work that developed a new approach to immobilize mPEG on an amine-activated Nylon 6 surface. Herein, we compare functionalized samples of Nylon 6 together with samples additionally containing copper nanoparticles (Cu NPs, size 40–60 nm) physisorbed on a modified surface. Modified samples were analyzed via different techniques including water contact angle measurements, atomic force microscopy and scanning electron microscopy associated with energy dispersive Xray spectroscopy. The copper functionalized samples showed high antibacterial efficacy against Gram-positive Staphylococcus aureus and Gram-negative Pseudomonas aeruginosa. Moreover, most of the prepared samples were cytocompatible.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10401 - Organic chemistry

Projekt

<a href="/cs/project/EF16_019%2F0000843" target="_blank" >EF16_019/0000843: Hybridní materiály pro hierarchické struktury</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Polymer Journal

ISSN

0014-3057

e-ISSN

—

Svazek periodika

122

Číslo periodika v rámci svazku

1(1)

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

12

Strana od-do

—

Kód UT WoS článku

000509784900012

EID výsledku v databázi Scopus

2-s2.0-85076624002