Effective poly(ethylene glycol) methyl ether grafting technique onto Nylon 6 surface to achieve resistance against pathogenic bacteria Staphylococcus aureus and Pseudomonas aeruginosa
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24220%2F18%3A00005552" target="_blank" >RIV/46747885:24220/18:00005552 - isvavai.cz</a>
Nalezeny alternativní kódy
RIV/46747885:24410/18:00005552 RIV/46747885:24510/18:00005552 RIV/46747885:24620/18:00005552 RIV/60461373:22340/18:43916387
Výsledek na webu
<a href="https://link.springer.com/article/10.1007/s10853-018-2636-2" target="_blank" >https://link.springer.com/article/10.1007/s10853-018-2636-2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10853-018-2636-2" target="_blank" >10.1007/s10853-018-2636-2</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Effective poly(ethylene glycol) methyl ether grafting technique onto Nylon 6 surface to achieve resistance against pathogenic bacteria Staphylococcus aureus and Pseudomonas aeruginosa
Popis výsledku v původním jazyce
Our study is focused on an efficient reduction of amide functional groups to secondary amine on Nylon 6 surface with borane–tetrahydrofuran (BH3–THF) complex, followed by N-alkylation with benzyl chloride (C6H5CH2Cl) which has been successfully used as a model system for further grafting of the reduced Nylon 6 surface by poly(ethylene glycol) methyl ether tosylate (Me-PEG-OTs). The amine-activated surface has been obtained by treatment of reduced Nylon 6 with n-butyllithium or tert-butyllithium in THF. Modified Nylon 6 has been found to be antibacterial particularly due to the presence of hydrophilic poly(ethylene glycol) methyl ether (H3C-PEG) chains. The surface modifications were successfully characterized by various techniques. Water contact angle and free surface energy analyses indicated a significant change in the surface morphology. It was further supported by scanning electron microscopy, atomic force microscopy, X-ray photoelectron spectroscopy, Fourier-transform infrared spectroscopy and Raman spectroscopy. Finally, antibacterial tests were performed against two pathogenic bacterial strains Pseudomonas aeruginosa (CCM 3955) and Staphylococcus aureus (CCM 3953).
Název v anglickém jazyce
Effective poly(ethylene glycol) methyl ether grafting technique onto Nylon 6 surface to achieve resistance against pathogenic bacteria Staphylococcus aureus and Pseudomonas aeruginosa
Popis výsledku anglicky
Our study is focused on an efficient reduction of amide functional groups to secondary amine on Nylon 6 surface with borane–tetrahydrofuran (BH3–THF) complex, followed by N-alkylation with benzyl chloride (C6H5CH2Cl) which has been successfully used as a model system for further grafting of the reduced Nylon 6 surface by poly(ethylene glycol) methyl ether tosylate (Me-PEG-OTs). The amine-activated surface has been obtained by treatment of reduced Nylon 6 with n-butyllithium or tert-butyllithium in THF. Modified Nylon 6 has been found to be antibacterial particularly due to the presence of hydrophilic poly(ethylene glycol) methyl ether (H3C-PEG) chains. The surface modifications were successfully characterized by various techniques. Water contact angle and free surface energy analyses indicated a significant change in the surface morphology. It was further supported by scanning electron microscopy, atomic force microscopy, X-ray photoelectron spectroscopy, Fourier-transform infrared spectroscopy and Raman spectroscopy. Finally, antibacterial tests were performed against two pathogenic bacterial strains Pseudomonas aeruginosa (CCM 3955) and Staphylococcus aureus (CCM 3953).
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10404 - Polymer science
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of Materials Science
ISSN
0022-2461
e-ISSN
—
Svazek periodika
53
Číslo periodika v rámci svazku
20
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
17
Strana od-do
14104-14120
Kód UT WoS článku
000440287100005
EID výsledku v databázi Scopus
2-s2.0-85049084135