The combination of meltblown technology and electrospinning – The influence of the ratio of micro and nanofibers on cell viability

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F16%3A00000587" target="_blank" >RIV/46747885:24410/16:00000587 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/46747885:24620/16:00000587

Výsledek na webu

<a href="http://www.sciencedirect.com/science/article/pii/S0167577X16303093" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0167577X16303093</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.matlet.2016.02.147" target="_blank" >10.1016/j.matlet.2016.02.147</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The combination of meltblown technology and electrospinning – The influence of the ratio of micro and nanofibers on cell viability

Popis výsledku v původním jazyce

This study describes the production, testing and characterization of biodegradable scaffolds for bone tissue, which consist of the exact ratio of meltblown microfibers and nanofibers produced through the electrostatic field. All fibrous materials were produced from polycaprolactone. Three kinds of materials were prepared in the experiment with the same area density and with different well-defined ratio of microfibers as a mechanical component and nanofibers as a cells adherent component. All prepared materials showed optimum porosity of the inner structure for cell proliferation and in comparison to the materials with nanofibers they had good mechanical properties. Important structural properties and homogenity of each material were observed by electron microscopy and analyzed by image analysis. The effect of various ratios of microfibers and nanofibers on adhesion and proliferation of osteoblasts in-vitro was characterized.

Název v anglickém jazyce

The combination of meltblown technology and electrospinning – The influence of the ratio of micro and nanofibers on cell viability

Popis výsledku anglicky

This study describes the production, testing and characterization of biodegradable scaffolds for bone tissue, which consist of the exact ratio of meltblown microfibers and nanofibers produced through the electrostatic field. All fibrous materials were produced from polycaprolactone. Three kinds of materials were prepared in the experiment with the same area density and with different well-defined ratio of microfibers as a mechanical component and nanofibers as a cells adherent component. All prepared materials showed optimum porosity of the inner structure for cell proliferation and in comparison to the materials with nanofibers they had good mechanical properties. Important structural properties and homogenity of each material were observed by electron microscopy and analyzed by image analysis. The effect of various ratios of microfibers and nanofibers on adhesion and proliferation of osteoblasts in-vitro was characterized.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JJ - Ostatní materiály

OECD FORD obor

—

Projekt

<a href="/cs/project/ED3.1.00%2F14.0308" target="_blank" >ED3.1.00/14.0308: Nanovlákenné materiály pro tkáňové inženýrství</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials Letters

ISSN

0167-577X

e-ISSN

—

Svazek periodika

173

Číslo periodika v rámci svazku

June

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

5

Strana od-do

153-157

Kód UT WoS článku

000374325900038

EID výsledku v databázi Scopus

2-s2.0-84961168428