The combination of meltblown and electrospinning for tissue engineering

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F16%3A00000867" target="_blank" >RIV/46747885:24410/16:00000867 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The combination of meltblown and electrospinning for tissue engineering

Popis výsledku v původním jazyce

Summer school of regenerative Nano-Medicine - From Advanced Delivery Systems to Electronic -Based Devices, 19-23 June 2016, Tel Aviv University, Tel Aviv, Israel Poster and oral presentationAbstractThis study describes the production, testing and characterization of biodegradable cellular 3D scaffolds for tissue engineering, which are consisting of a mixture of microfibers produced by meltblown technology and nanofibers produced by electrospinning. All the fibrous materials are produced from polycaprolactone. The prepared materials showed the optimal porosity for the inner cell prolifaration and sompared to the a purely nanofibrous materials have good mechanical properties. Useful structural properties and homogenity of the material are described by electron microscopy and image analysis. Was characterized the biocompatibility and cells prolifaration bi in - vitro testing of the different ratio of microfibers and nanofibers on adhesion and proliferation of osteoblasts in - vivo while maintaining good mechanical strength. Subsequent in - vivo testing on celected biological models confirmed a solid materials ability to create required tissue for bone regeneration or thymus organoid creating.

Název v anglickém jazyce

The combination of meltblown and electrospinning for tissue engineering

Popis výsledku anglicky

Summer school of regenerative Nano-Medicine - From Advanced Delivery Systems to Electronic -Based Devices, 19-23 June 2016, Tel Aviv University, Tel Aviv, Israel Poster and oral presentationAbstractThis study describes the production, testing and characterization of biodegradable cellular 3D scaffolds for tissue engineering, which are consisting of a mixture of microfibers produced by meltblown technology and nanofibers produced by electrospinning. All the fibrous materials are produced from polycaprolactone. The prepared materials showed the optimal porosity for the inner cell prolifaration and sompared to the a purely nanofibrous materials have good mechanical properties. Useful structural properties and homogenity of the material are described by electron microscopy and image analysis. Was characterized the biocompatibility and cells prolifaration bi in - vitro testing of the different ratio of microfibers and nanofibers on adhesion and proliferation of osteoblasts in - vivo while maintaining good mechanical strength. Subsequent in - vivo testing on celected biological models confirmed a solid materials ability to create required tissue for bone regeneration or thymus organoid creating.

Druh

O - Ostatní výsledky

CEP obor

JJ - Ostatní materiály

OECD FORD obor

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Projekt

<a href="/cs/project/ED3.1.00%2F14.0308" target="_blank" >ED3.1.00/14.0308: Nanovlákenné materiály pro tkáňové inženýrství</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů