A model of tissue perfusion based on homogenization of Darcy flow in double-porous layered medium

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F11%3A43897259" target="_blank" >RIV/49777513:23520/11:43897259 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

A model of tissue perfusion based on homogenization of Darcy flow in double-porous layered medium

Popis výsledku v původním jazyce

We developed a model of homogenized perfusion in a medium constituted by several transversely partially periodic layers, which enables us to approximate flow through different hierarchies of the porosity. We focus on modeling the perfusion of tissue parenchyma, being motivated by medical applications: a) the assessment of the local cerebral blood flow and b) the liver segmentation. At the level of small vessels and microvessels, the perfusion can be described using the Darcy flow in double porous structure consisting of 3 compartments: two mutually disconnected channels (small arteries and veins) and the matrix (microvessels and capillaries), represented as the dual porosity, where the permeability is decreasing with the scale parameter.

Název v anglickém jazyce

A model of tissue perfusion based on homogenization of Darcy flow in double-porous layered medium

Popis výsledku anglicky

We developed a model of homogenized perfusion in a medium constituted by several transversely partially periodic layers, which enables us to approximate flow through different hierarchies of the porosity. We focus on modeling the perfusion of tissue parenchyma, being motivated by medical applications: a) the assessment of the local cerebral blood flow and b) the liver segmentation. At the level of small vessels and microvessels, the perfusion can be described using the Darcy flow in double porous structure consisting of 3 compartments: two mutually disconnected channels (small arteries and veins) and the matrix (microvessels and capillaries), represented as the dual porosity, where the permeability is decreasing with the scale parameter.

Druh

O - Ostatní výsledky

CEP obor

BK - Mechanika tekutin

OECD FORD obor

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Projekt

<a href="/cs/project/GA106%2F09%2F0740" target="_blank" >GA106/09/0740: Mikrostrukturálně orientované hierarchické modelování prokrvení mozku pro vyhodnocení CT perfúzního vyšetření</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů