Computational homogenization of tissue parenchyma using layer-wise decomposition

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F12%3A43916259" target="_blank" >RIV/49777513:23520/12:43916259 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Computational homogenization of tissue parenchyma using layer-wise decomposition

Popis výsledku v původním jazyce

The mathematical model of perfusion through different hierarchies of tissue parenchyma can be derived using the asymptotic homogenization technique which is applied to the Darcy flow problem in the multi-compartment medium with a dual porosity. This approach gives us the tool for decomposition of a 3D volume into a finite number of homogenized 2D layers coupled together by conditions governing the fluid exchange between them. The layer-wise decomposition allows us to approximate the hierarchical structure of the perfusion tree by several homogenized layers with distinct material properties and topology of the underlying microstructure. The tissue parenchyma can be considered as a structure consisting of small arteries and veins connected together by microvessels and capillaries. In the model, the arteries and veins are represented by two disconnected channels. Fluid can flow between these two primary porosities through the matrix representing the dual porosity where the permeability is

Název v anglickém jazyce

Computational homogenization of tissue parenchyma using layer-wise decomposition

Popis výsledku anglicky

The mathematical model of perfusion through different hierarchies of tissue parenchyma can be derived using the asymptotic homogenization technique which is applied to the Darcy flow problem in the multi-compartment medium with a dual porosity. This approach gives us the tool for decomposition of a 3D volume into a finite number of homogenized 2D layers coupled together by conditions governing the fluid exchange between them. The layer-wise decomposition allows us to approximate the hierarchical structure of the perfusion tree by several homogenized layers with distinct material properties and topology of the underlying microstructure. The tissue parenchyma can be considered as a structure consisting of small arteries and veins connected together by microvessels and capillaries. In the model, the arteries and veins are represented by two disconnected channels. Fluid can flow between these two primary porosities through the matrix representing the dual porosity where the permeability is

Druh

O - Ostatní výsledky

CEP obor

BI - Akustika a kmity

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů