Modeling of dynamic perfusion test using a two-scale model of tissue parenchyma with layer-wise decomposition

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F12%3A43915718" target="_blank" >RIV/49777513:23520/12:43915718 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Modeling of dynamic perfusion test using a two-scale model of tissue parenchyma with layer-wise decomposition

Popis výsledku v původním jazyce

We developed a model of homogenized perfusion in the 3-compartment medium constituted by several transversely periodic layers, which enable us to approximate flow through different hierarchies of the porosity. A 3D layered structure can be replaced by afinite number of 2D "homogenized layers" coupled by conditions governing the fluid exchange between them. Each layer is assumed to have a locally periodic structure generated by the reference periodic cell. Using this cell, homogenized coefficients relevant to the macroscopic level can be calculated. However, using generalized coupling conditions for geometrically non-matching layers along their interfaces, this approach allows us to approximate the hierarchical structure of the perfusion tree: in eachlayer the periodic microstructure can be different and can be of different size. Then also more separated channel porosities in each layer can be considered. Using the macroscopic flow response, pressures, related perfusion velocities and

Název v anglickém jazyce

Modeling of dynamic perfusion test using a two-scale model of tissue parenchyma with layer-wise decomposition

Popis výsledku anglicky

We developed a model of homogenized perfusion in the 3-compartment medium constituted by several transversely periodic layers, which enable us to approximate flow through different hierarchies of the porosity. A 3D layered structure can be replaced by afinite number of 2D "homogenized layers" coupled by conditions governing the fluid exchange between them. Each layer is assumed to have a locally periodic structure generated by the reference periodic cell. Using this cell, homogenized coefficients relevant to the macroscopic level can be calculated. However, using generalized coupling conditions for geometrically non-matching layers along their interfaces, this approach allows us to approximate the hierarchical structure of the perfusion tree: in eachlayer the periodic microstructure can be different and can be of different size. Then also more separated channel porosities in each layer can be considered. Using the macroscopic flow response, pressures, related perfusion velocities and

Druh

O - Ostatní výsledky

CEP obor

BK - Mechanika tekutin

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů