D-Lactic Acid as a Metabolite: Toxicology, Diagnosis, and Detection

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F20%3A00555937" target="_blank" >RIV/60162694:G44__/20:00555937 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.hindawi.com/journals/biomed/" target="_blank" >http://www.hindawi.com/journals/biomed/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2020/3419034" target="_blank" >10.1155/2020/3419034</a>

Jazyk výsledku

angličtina

Název v původním jazyce

D-Lactic Acid as a Metabolite: Toxicology, Diagnosis, and Detection

Popis výsledku v původním jazyce

Two enantiomers of lactic acid exist. While L-lactic acid is a common compound of human metabolism, D-lactic acid is produced by some strains of microorganism or by some less relevant metabolic pathways. While L-lactic acid is an endogenous compound, D-lactic acid is a harmful enantiomer. Exposure to D-lactic acid can happen by various ways including contaminated food and beverages and by microbiota during some pathological states like short bowel syndrome. The exposure to D-lactic acid cannot be diagnosed because the common analytical methods are not suitable for distinguishing between the two enantiomers. In this review, pathways for D-lactic acid, pathological processes, and diagnostical and analytical methods are introduced followed by figures and tables. The current literature is summarized and discussed.

Název v anglickém jazyce

D-Lactic Acid as a Metabolite: Toxicology, Diagnosis, and Detection

Popis výsledku anglicky

Two enantiomers of lactic acid exist. While L-lactic acid is a common compound of human metabolism, D-lactic acid is produced by some strains of microorganism or by some less relevant metabolic pathways. While L-lactic acid is an endogenous compound, D-lactic acid is a harmful enantiomer. Exposure to D-lactic acid can happen by various ways including contaminated food and beverages and by microbiota during some pathological states like short bowel syndrome. The exposure to D-lactic acid cannot be diagnosed because the common analytical methods are not suitable for distinguishing between the two enantiomers. In this review, pathways for D-lactic acid, pathological processes, and diagnostical and analytical methods are introduced followed by figures and tables. The current literature is summarized and discussed.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

20801 - Environmental biotechnology

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BioMed Research International

ISSN

2314-6133

e-ISSN

2314-6141

Svazek periodika

2020

Číslo periodika v rámci svazku

Jun

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

3419034

Kód UT WoS článku

000546074600001

EID výsledku v databázi Scopus

2-s2.0-85087553823