Vliv genisteinu a genistinu na meiotické zrání oocytů prasat

Kód výsledku v IS VaVaI

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RIV/60460709:41210/05:###11693

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The influence of genistein and genistin on the meiotic maturation of pig oocytes

Popis výsledku v původním jazyce

Phytoestrogens are natural plant substances structurally similar to endogenous estrogens. Genistein is the main phytoestrogen in soya. There are evidences it can affect meiotic maturation of pig oocytes. These effects are attributed to genistein abilityto inhibit tyrozin protein kinase activity. Genistin is an analog of genistein. It has also estrogenic activity but it lack the inhibitory activity for the tyrozin protein kinase. The aim of our study was to verify genistein and genistin effects on meiotic maturation of pig oocytes and to determine, if they are caused by tyrozin protein kinase inhibition or due to an estrogenic activity. Three experiments were performed: 1. Oocytes were cultivated for 24 hours in various concentration of genistein. 2. Oocytes were cultivated for 24 hours in medium with 80 ?g/ml of genistein, then washed and cultivated for another 24 hours in genistein free medium. 3. Oocytes were cultivated for 24 hours in various concentration of genistin. Genistein in

Název v anglickém jazyce

The influence of genistein and genistin on the meiotic maturation of pig oocytes

Popis výsledku anglicky

Phytoestrogens are natural plant substances structurally similar to endogenous estrogens. Genistein is the main phytoestrogen in soya. There are evidences it can affect meiotic maturation of pig oocytes. These effects are attributed to genistein abilityto inhibit tyrozin protein kinase activity. Genistin is an analog of genistein. It has also estrogenic activity but it lack the inhibitory activity for the tyrozin protein kinase. The aim of our study was to verify genistein and genistin effects on meiotic maturation of pig oocytes and to determine, if they are caused by tyrozin protein kinase inhibition or due to an estrogenic activity. Three experiments were performed: 1. Oocytes were cultivated for 24 hours in various concentration of genistein. 2. Oocytes were cultivated for 24 hours in medium with 80 ?g/ml of genistein, then washed and cultivated for another 24 hours in genistein free medium. 3. Oocytes were cultivated for 24 hours in various concentration of genistin. Genistein in

Druh

D - Stať ve sborníku

CEP obor

GG - Chov hospodářských zvířat

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Current Problems of Brreding, Health, Growth and Production of Pigs

ISBN

80-85645-50-5

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

257-260

Název nakladatele

Biologická fakulta

Místo vydání

České Budějovice

Místo konání akce

České Budějovice

Datum konání akce

9. 2. 2005

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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