Vliv zearalenonu na meiotické zrání oocytů prasete

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F05%3A11695" target="_blank" >RIV/60460709:41210/05:11695 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60460709:41210/05:###11695

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

The influence of zearalenone on the meiotic maturation of pig oocytes

Popis výsledku v původním jazyce

Mycoestrogens belong to the group of environmental estrogens. They represent a group of mycotoxins which can act as endogenous estrogens due to their binding ability with estrogen receptors, and thereby affect animals. The aim of our study was to verifyzearalenone effects on meiotic maturation of pig oocytes. Oocytes were cultivated in the M 199 medium under constant conditions of 39 şC and 5 % CO2 in the air for 24 hours to the MI stage. Various amounts of zearalenone (0, 6, 18, 36, 72 ?g/ml) were added to the medium. Zearalenone inhibited maturation of pig oocytes in the stage of germinal vesicle (GV) and late diakinesis (LD) in a dose-dependent manner. The highest effectiveness was observed in the concentration 36 ?g/ml of the medium (GV 52 %, LD 37 %). The zearalenone dose of 72 ?g/ml already had a toxic effect, as many degenerate oocytes were present. The results of our study show that zearalenone can negatively affect maturation of mammalian oocytes and thus disturb fertility of

Název v anglickém jazyce

The influence of zearalenone on the meiotic maturation of pig oocytes

Popis výsledku anglicky

Mycoestrogens belong to the group of environmental estrogens. They represent a group of mycotoxins which can act as endogenous estrogens due to their binding ability with estrogen receptors, and thereby affect animals. The aim of our study was to verifyzearalenone effects on meiotic maturation of pig oocytes. Oocytes were cultivated in the M 199 medium under constant conditions of 39 şC and 5 % CO2 in the air for 24 hours to the MI stage. Various amounts of zearalenone (0, 6, 18, 36, 72 ?g/ml) were added to the medium. Zearalenone inhibited maturation of pig oocytes in the stage of germinal vesicle (GV) and late diakinesis (LD) in a dose-dependent manner. The highest effectiveness was observed in the concentration 36 ?g/ml of the medium (GV 52 %, LD 37 %). The zearalenone dose of 72 ?g/ml already had a toxic effect, as many degenerate oocytes were present. The results of our study show that zearalenone can negatively affect maturation of mammalian oocytes and thus disturb fertility of

Druh

D - Stať ve sborníku

CEP obor

GG - Chov hospodářských zvířat

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

The 4th Symposium of the Society for Biology of Reproduction

ISBN

83-60127-55-7

ISSN

—

e-ISSN

—

Počet stran výsledku

1

Strana od-do

125-125

Název nakladatele

Deparment of Animal Physiology, University of Agriculture, Krakow

Místo vydání

Krakow, Polsko

Místo konání akce

Krakow, Polsko

Datum konání akce

22. 9. 2005

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

—