Fazolový alfa-amylázový inhibitor: Perspektivní transgen pro rostlinné biotechnologické aplikace

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F05%3A11972" target="_blank" >RIV/60460709:41210/05:11972 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Bean alpha-amylase inhibitor: A perspective transgene for plant biotechnology applications.

Popis výsledku v původním jazyce

The &#945;-amylase inhibitors (AIs) became a new tool for regulation of important pathological processes through the application of plant biotechnologies. First, the plant AIs represent promising biopesticides for the development of resistant GM crops. This strategy is safe for humans since AIs naturally occur in crops as defensive proteins targeted against the digestive amylases of insects. The second emerging field is a potential use of orally given AIs in medicine in suppressing postprandial glucoselevels of diabetic patients. In this work, we present an analysis of inhibitory selectivity of &#945;AI-1 from common bean (Phaseolus vulgaris cv. Magna). The inhibitory potential of &#945;AI-1 was screened with a panel of the digestive &#945;-amylases from 30 species of insects, mites, gastropod, annelid worm, nematode and fungal phytopathogens with a focus on agricultural pests and important model species. Based on results of the in vitro analysis, the in vivo activity of the ingested

Název v anglickém jazyce

Bean alpha-amylase inhibitor: A perspective transgene for plant biotechnology applications.

Popis výsledku anglicky

The &#945;-amylase inhibitors (AIs) became a new tool for regulation of important pathological processes through the application of plant biotechnologies. First, the plant AIs represent promising biopesticides for the development of resistant GM crops. This strategy is safe for humans since AIs naturally occur in crops as defensive proteins targeted against the digestive amylases of insects. The second emerging field is a potential use of orally given AIs in medicine in suppressing postprandial glucoselevels of diabetic patients. In this work, we present an analysis of inhibitory selectivity of &#945;AI-1 from common bean (Phaseolus vulgaris cv. Magna). The inhibitory potential of &#945;AI-1 was screened with a panel of the digestive &#945;-amylases from 30 species of insects, mites, gastropod, annelid worm, nematode and fungal phytopathogens with a focus on agricultural pests and important model species. Based on results of the in vitro analysis, the in vivo activity of the ingested

Druh

D - Stať ve sborníku

CEP obor

GF - Choroby, škůdci, plevely a ochrana rostlin

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

From Laboratory to Business. Recent Advances in Plant Biotechnology. České Budějovice

ISBN

80-86778-16-9

ISSN

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e-ISSN

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Počet stran výsledku

1

Strana od-do

16-16

Název nakladatele

Institute of Plant Molecular Biology ASCR

Místo vydání

České Budějovice

Místo konání akce

České Budějovice

Datum konání akce

12. 9. 2005

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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