The evalution of the melanocortin-4 receptor of the ryanodine-1 receptor and the interaction between this genes on carcass trait in pigs

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F10%3A47723" target="_blank" >RIV/60460709:41210/10:47723 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

čeština

Název v původním jazyce

The evalution of the melanocortin-4 receptor of the ryanodine-1 receptor and the interaction between this genes on carcass trait in pigs

Popis výsledku v původním jazyce

The melanocortin-4 receptor (MC4R) plays an important role in the control of mammalian energy homeostasis. In this context, many researches noted that a variant of the candidate gene MC4R may explain the significant variation in backfat thickness, growthrate, and feed intake in commercial pig hybrids. The aim of this study was demonstrated the effect mutation AF087937:c.746G>A in the MC4R gene, the effect causal mutation C1843T in the RYR1 gene and the interaction between these genes. In this study wasfound the significant influence of allele G in the MC4R gene and of allele n in the RYR1 gene on lean meat. Moreover, we did not find the interaction between these on killing out percentage. Also we assume, that allele G have influence on higher lean meat. In the contrary, we did not find an evidential influence of c.746G>A in the MC4R gene on fatness. We detected the significant influence only on backfat thickness and we did not find any trend of MC4R gene on fatness.

Název v anglickém jazyce

THE EVALUATION OF THE MELANOCORTIN-4 RECEPTOR OF THE RYANODINE-1 RECEPTOR AND THE INTERACTION BETWEEN THIS GENES ON CARCASS TRAIT IN PIGS

Popis výsledku anglicky

The melanocortin-4 receptor (MC4R) plays an important role in the control of mammalian energy homeostasis. In this context, many researches noted that a variant of the candidate gene MC4R may explain the significant variation in backfat thickness, growthrate, and feed intake in commercial pig hybrids. The aim of this study was demonstrated the effect mutation AF087937:c.746G>A in the MC4R gene, the effect causal mutation C1843T in the RYR1 gene and the interaction between these genes. In this study wasfound the significant influence of allele G in the MC4R gene and of allele n in the RYR1 gene on lean meat. Moreover, we did not find the interaction between these on killing out percentage. Also we assume, that allele G have influence on higher lean meat. In the contrary, we did not find an evidential influence of c.746G>A in the MC4R gene on fatness. We detected the significant influence only on backfat thickness and we did not find any trend of MC4R gene on fatness.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GG - Chov hospodářských zvířat

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Research in Pig Breeding - Výzkum v chovu prasat

ISSN

1802-7547

e-ISSN

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Svazek periodika

4

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

5

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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