Organo-sulphur garlic compounds influence viability of mammalian cells. A review.
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F18%3A74027" target="_blank" >RIV/60460709:41210/18:74027 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.2478/sab-2018-0002" target="_blank" >http://dx.doi.org/10.2478/sab-2018-0002</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2478/sab-2018-0002" target="_blank" >10.2478/sab-2018-0002</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Organo-sulphur garlic compounds influence viability of mammalian cells. A review.
Popis výsledku v původním jazyce
Garlic it is still in the centre of interest for its therapeutic effects. Currently, attention is focused on physiological effects of organo-sulphur garlic compounds, as alliin, allicin, diallyl sulfide (DAS), diallyl disulfide (DADS), diallyl trisulfide (DATS) and S-allyl cysteine (SAC), particularly on their antioxidant and anticancerogenic effects. SAC has been studied for its ability to decrease the production of reactive oxygen species by modulation of the cell glutathione level together with antioxidative enzyme activity, and by improvement of mitochondrial functions. The main mechanism of DAS, DADS, and DATS is induction of the internal apoptotic pathway. Garlic compounds have ability to interfere with the signalling pathways of small gaseous signalling molecules known as gasotransmitters, nitric oxide (NO), hydrogen sulphide (H2S) and carbon monoxide (CO). The review presents the effect of garlic compounds on cellular oxidative stress, intrinsic apoptotic, and gasotransmitter pathways and com
Název v anglickém jazyce
Organo-sulphur garlic compounds influence viability of mammalian cells. A review.
Popis výsledku anglicky
Garlic it is still in the centre of interest for its therapeutic effects. Currently, attention is focused on physiological effects of organo-sulphur garlic compounds, as alliin, allicin, diallyl sulfide (DAS), diallyl disulfide (DADS), diallyl trisulfide (DATS) and S-allyl cysteine (SAC), particularly on their antioxidant and anticancerogenic effects. SAC has been studied for its ability to decrease the production of reactive oxygen species by modulation of the cell glutathione level together with antioxidative enzyme activity, and by improvement of mitochondrial functions. The main mechanism of DAS, DADS, and DATS is induction of the internal apoptotic pathway. Garlic compounds have ability to interfere with the signalling pathways of small gaseous signalling molecules known as gasotransmitters, nitric oxide (NO), hydrogen sulphide (H2S) and carbon monoxide (CO). The review presents the effect of garlic compounds on cellular oxidative stress, intrinsic apoptotic, and gasotransmitter pathways and com
Klasifikace
Druh
J<sub>SC</sub> - Článek v periodiku v databázi SCOPUS
CEP obor
—
OECD FORD obor
30105 - Physiology (including cytology)
Návaznosti výsledku
Projekt
—
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Scientia Agriculturae Bohemica
ISSN
1211-3174
e-ISSN
—
Svazek periodika
49
Číslo periodika v rámci svazku
1
Stát vydavatele periodika
CZ - Česká republika
Počet stran výsledku
8
Strana od-do
9-16
Kód UT WoS článku
—
EID výsledku v databázi Scopus
2-s2.0-85045880212