Anti-staphylococcal activity, cytotoxicity, and chemical composition of hexane extracts from arils and seeds of two Samoan Myristica spp

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F21%3A88191" target="_blank" >RIV/60460709:41210/21:88191 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60460709:41340/21:88191

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S025462992100017X" target="_blank" >https://www.sciencedirect.com/science/article/pii/S025462992100017X</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.sajb.2021.01.009" target="_blank" >10.1016/j.sajb.2021.01.009</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Anti-staphylococcal activity, cytotoxicity, and chemical composition of hexane extracts from arils and seeds of two Samoan Myristica spp

Popis výsledku v původním jazyce

Hexane extracts derived from the arils and seeds of two Samoan indigenous plant species, Myristica hypargyraea A. Gray and Myristica inutilis Rich ex A. Gray, were assessed for their in vitro anti-staphylococcal effect using a broth microdilution assay. Additionally, their cytotoxic activity against human colon cancer and normal intestinal cell lines was determined. In this study, all plant extracts tested showed a certain degree of growth-inhibitory effect against various strains of Staphylococcus aureus with minimum inhibitory concentrations (MICs) ranging from 8 to 1,024 g mL. The aril extract of M. hypargyraea possessed the highest antibacterial activity with MIC value 8 ug mL against one standard strain and three clinical isolates of S. aureus, the effective concentrations of this extract were found to be safe for the intestinal cells. The aril extract of M. inutilis showed the highest selective antiproliferative effect on intestinal cancer cells with a lower toxicity to normal cell lines. Usin

Název v anglickém jazyce

Anti-staphylococcal activity, cytotoxicity, and chemical composition of hexane extracts from arils and seeds of two Samoan Myristica spp

Popis výsledku anglicky

Hexane extracts derived from the arils and seeds of two Samoan indigenous plant species, Myristica hypargyraea A. Gray and Myristica inutilis Rich ex A. Gray, were assessed for their in vitro anti-staphylococcal effect using a broth microdilution assay. Additionally, their cytotoxic activity against human colon cancer and normal intestinal cell lines was determined. In this study, all plant extracts tested showed a certain degree of growth-inhibitory effect against various strains of Staphylococcus aureus with minimum inhibitory concentrations (MICs) ranging from 8 to 1,024 g mL. The aril extract of M. hypargyraea possessed the highest antibacterial activity with MIC value 8 ug mL against one standard strain and three clinical isolates of S. aureus, the effective concentrations of this extract were found to be safe for the intestinal cells. The aril extract of M. inutilis showed the highest selective antiproliferative effect on intestinal cancer cells with a lower toxicity to normal cell lines. Usin

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10611 - Plant sciences, botany

Projekt

<a href="/cs/project/EF16_019%2F0000845" target="_blank" >EF16_019/0000845: Centrum pro studium vzniku a transformací nutričně významných látek v potravním řetězci v interakci s potenciálně rizikovými látkami antropogenního původu: komplexní posouzení rizika kontaminace půdy pro kvalitu zemědělské produkce</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

South African Journal of Botany

ISSN

0254-6299

e-ISSN

1727-9321

Svazek periodika

139

Číslo periodika v rámci svazku

jul

Stát vydavatele periodika

ZA - Jihoafrická republika

Počet stran výsledku

5

Strana od-do

1-5

Kód UT WoS článku

000662214400001

EID výsledku v databázi Scopus

2-s2.0-85100384325