Amine functionalized carbon nanoparticles grafted biopolymer for cell adhesion and proliferation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F15%3A43900453" target="_blank" >RIV/60461373:22310/15:43900453 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Amine functionalized carbon nanoparticles grafted biopolymer for cell adhesion and proliferation

Popis výsledku v původním jazyce

Various carbon nanostructures are widely researched for use in number of medical applications. We evaluated the surface properties and cell-substrate interactions of three types of amine functionalized carbon nanoparticles (CNPs) grafted on biopolymer film. Poly-L-lactic acid, in form of polymer film, was treated in an inert argon plasma discharge and, subsequently, grafted with functionalized carbon nanoparticles. Selected samples were thermally stressed during or following the grafting procedure. Thesurface properties were studied using multiple methods, including goniometry, atomic force microscopy and X-ray photoelectron spectroscopy. Cell-substrate interactions were determined in vitro by studying adhesion, proliferation and viability of vascularsmooth muscle cells (VSMCs) from the aorta of a rat. Cell-substrate interactions on pristine and modified substrates were compared to standard tissue culture polystyrene (TCPS). Our results show that CNPs affect surface morphology and we

Název v anglickém jazyce

Amine functionalized carbon nanoparticles grafted biopolymer for cell adhesion and proliferation

Popis výsledku anglicky

Various carbon nanostructures are widely researched for use in number of medical applications. We evaluated the surface properties and cell-substrate interactions of three types of amine functionalized carbon nanoparticles (CNPs) grafted on biopolymer film. Poly-L-lactic acid, in form of polymer film, was treated in an inert argon plasma discharge and, subsequently, grafted with functionalized carbon nanoparticles. Selected samples were thermally stressed during or following the grafting procedure. Thesurface properties were studied using multiple methods, including goniometry, atomic force microscopy and X-ray photoelectron spectroscopy. Cell-substrate interactions were determined in vitro by studying adhesion, proliferation and viability of vascularsmooth muscle cells (VSMCs) from the aorta of a rat. Cell-substrate interactions on pristine and modified substrates were compared to standard tissue culture polystyrene (TCPS). Our results show that CNPs affect surface morphology and we

Druh

D - Stať ve sborníku

CEP obor

JJ - Ostatní materiály

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Nanocon 2015 7th international conference papers - full texts

ISBN

978-80-87294-59-8

ISSN

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e-ISSN

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Počet stran výsledku

6

Strana od-do

1-6

Název nakladatele

Tanger s.r.o.

Místo vydání

Ostrava

Místo konání akce

Brno

Datum konání akce

14. 10. 2015

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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