Rapid and simple method for determination of hexabromocyclododecanes and other LC-MS-MS amenable brominated flame retardants in fish

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F13%3A43896641" target="_blank" >RIV/60461373:22330/13:43896641 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00216-013-7076-x" target="_blank" >http://dx.doi.org/10.1007/s00216-013-7076-x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00216-013-7076-x" target="_blank" >10.1007/s00216-013-7076-x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Rapid and simple method for determination of hexabromocyclododecanes and other LC-MS-MS amenable brominated flame retardants in fish

Popis výsledku v původním jazyce

In this study, a novel analytical approach for simultaneous determination of hexabromocyclododecane isomers (HBCDs), tetrabromobisphenol A (TBBPA), three brominated phenols, and four hydroxylated derivatives of polybrominated diphenyl ethers (OH-PBDEs) was developed and validated for muscle tissue of both lean and fatty fish. The rapid, simple, and high-throughput sample-preparation procedure was based on acetonitrile extraction then purification by dispersive solid-phase extraction (d-SPE) with a combination of C18 and primary?secondary amine (PSA) sorbents. Ultra-high performance liquid chromatography (UHPLC) coupled to tandem mass spectrometry (MS?MS) was used for identification and quantification of the analytes. Method recovery for both matrices ranged from 80 to 115 % with relative standard deviations (RSDs) {13 % for all analytes. Limits of quantification (LOQs) were in the range 0.1?1 ?g kg?1 wet weight. The validated method was used for analysis of brominated compounds in 32 f

Název v anglickém jazyce

Rapid and simple method for determination of hexabromocyclododecanes and other LC-MS-MS amenable brominated flame retardants in fish

Popis výsledku anglicky

In this study, a novel analytical approach for simultaneous determination of hexabromocyclododecane isomers (HBCDs), tetrabromobisphenol A (TBBPA), three brominated phenols, and four hydroxylated derivatives of polybrominated diphenyl ethers (OH-PBDEs) was developed and validated for muscle tissue of both lean and fatty fish. The rapid, simple, and high-throughput sample-preparation procedure was based on acetonitrile extraction then purification by dispersive solid-phase extraction (d-SPE) with a combination of C18 and primary?secondary amine (PSA) sorbents. Ultra-high performance liquid chromatography (UHPLC) coupled to tandem mass spectrometry (MS?MS) was used for identification and quantification of the analytes. Method recovery for both matrices ranged from 80 to 115 % with relative standard deviations (RSDs) {13 % for all analytes. Limits of quantification (LOQs) were in the range 0.1?1 ?g kg?1 wet weight. The validated method was used for analysis of brominated compounds in 32 f

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GM - Potravinářství

OECD FORD obor

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Projekt

<a href="/cs/project/7E08068" target="_blank" >7E08068: CONtaminants in Food and Feed: Inexpensive DEtectioN for Control of Exposure</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Analytical and Bioanalytical Chemistry

ISSN

1618-2642

e-ISSN

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Svazek periodika

405

Číslo periodika v rámci svazku

24

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

11

Strana od-do

7829-7839

Kód UT WoS článku

000324109400024

EID výsledku v databázi Scopus

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