Comprehensive assessment of bioactive secondary metabolites in a set of aqueous extracts from agrimony (Agrimonia eupatoria L.)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F22%3A43925446" target="_blank" >RIV/60461373:22330/22:43925446 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Comprehensive assessment of bioactive secondary metabolites in a set of aqueous extracts from agrimony (Agrimonia eupatoria L.)

Popis výsledku v původním jazyce

Agrimony (Agrimonia eupatoria L.) is a medicinal plant widely used in traditional medicine. Nowadays, homemade herbal extracts are gaining growing popularity. Aqueous agrimony extracts are mainly used for rinsing wounds, alternatively, dried plant is used as tea. These products have positive effects on human health and body (antioxidant activity, anti-inflammatory effect or hepatoprotective effect) thanks to the content of several bioactive compounds such as flavonoids, phenolic acids or tannins. In this study, “homemade” aqueous extracts from agrimony herbs collected at different locations, differently processed (dried, fresh) and picked in various vegetation states were prepared and targeted screening of polyphenol compounds with the reversed phase ultra-high-performance liquid chromatography coupled with high-resolution tandem mass spectrometry (UHPLC-HRMS/MS) was carried out. For the purpose of aqueous extracts screening and interesting bioactive metabolites identification, an in-house spectral library of more than 500 polyphenolic compounds occurring in plants was created. In total, 62 compounds were identified. The samples did not differ significantly in the type of bioactive compounds, differences were only in the occurrence of some individual polyphenols depending on a geographical origin of respective sample. In the samples from the last vegetation state (senescence) was identified significantly less compounds and their profiles differed in comparison with other samples.

Název v anglickém jazyce

Comprehensive assessment of bioactive secondary metabolites in a set of aqueous extracts from agrimony (Agrimonia eupatoria L.)

Popis výsledku anglicky

Agrimony (Agrimonia eupatoria L.) is a medicinal plant widely used in traditional medicine. Nowadays, homemade herbal extracts are gaining growing popularity. Aqueous agrimony extracts are mainly used for rinsing wounds, alternatively, dried plant is used as tea. These products have positive effects on human health and body (antioxidant activity, anti-inflammatory effect or hepatoprotective effect) thanks to the content of several bioactive compounds such as flavonoids, phenolic acids or tannins. In this study, “homemade” aqueous extracts from agrimony herbs collected at different locations, differently processed (dried, fresh) and picked in various vegetation states were prepared and targeted screening of polyphenol compounds with the reversed phase ultra-high-performance liquid chromatography coupled with high-resolution tandem mass spectrometry (UHPLC-HRMS/MS) was carried out. For the purpose of aqueous extracts screening and interesting bioactive metabolites identification, an in-house spectral library of more than 500 polyphenolic compounds occurring in plants was created. In total, 62 compounds were identified. The samples did not differ significantly in the type of bioactive compounds, differences were only in the occurrence of some individual polyphenols depending on a geographical origin of respective sample. In the samples from the last vegetation state (senescence) was identified significantly less compounds and their profiles differed in comparison with other samples.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10700 - Other natural sciences

Projekt

<a href="/cs/project/LM2018100" target="_blank" >LM2018100: Infrastruktura pro propagaci metrologie v potravinářství a výživě v České republice</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů