Impact of Species, Growth Conditions, and Plant Processing on the Phytochemistry and Antimicrobial Activity of Agrimonia Extracts

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43510%2F25%3A43927358" target="_blank" >RIV/62156489:43510/25:43927358 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60461373:22330/25:43933110

Výsledek na webu

<a href="https://doi.org/10.1002/cbdv.202501283" target="_blank" >https://doi.org/10.1002/cbdv.202501283</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/cbdv.202501283" target="_blank" >10.1002/cbdv.202501283</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impact of Species, Growth Conditions, and Plant Processing on the Phytochemistry and Antimicrobial Activity of Agrimonia Extracts

Popis výsledku v původním jazyce

Agrimonia eupatoria L., a herb used in traditional medicine, contains numerous secondary metabolites with beneficial properties. However, its phytochemistry, and consequently bioactivity, can be strongly influenced by various cultivation and processing factors. This study evaluates the impact of growth locality, plant part, ontogenetic phase, and postharvest processing on the phytochemical composition and antimicrobial potential of two agrimony species: A. eupatoria and Agrimonia procera. A total of 94 herbal samples extracted with 40% aqueous ethanol were analyzed using ultrahigh-performance liquid chromatography and high-resolution tandem mass spectrometry and simultaneously tested against selected Gram-positive, Gram-negative, and anaerobic bacteria and yeasts. Targeted screening of bioactive polyphenols revealed significant differences between the agrimony species, with phloridzin and orientin/isoorientin identified as new potential chemotaxonomic markers. Notable differences were also observed between roots and aerial parts. Postharvest processing, particularly drying, proved to be another important factor, reducing the overall polyphenol content compared to fresh-frozen plant material. Although all extracts exhibited strong activity, especially against Gram-positive bacteria, the highest antimicrobial potential was observed in roots extracts rich in procyanidins and catechins. The findings of this study enhance the understanding of agrimony phytochemistry and its variability, thereby supporting the effective production of medicinal preparations with the desired therapeutic effects.

Název v anglickém jazyce

Impact of Species, Growth Conditions, and Plant Processing on the Phytochemistry and Antimicrobial Activity of Agrimonia Extracts

Popis výsledku anglicky

Agrimonia eupatoria L., a herb used in traditional medicine, contains numerous secondary metabolites with beneficial properties. However, its phytochemistry, and consequently bioactivity, can be strongly influenced by various cultivation and processing factors. This study evaluates the impact of growth locality, plant part, ontogenetic phase, and postharvest processing on the phytochemical composition and antimicrobial potential of two agrimony species: A. eupatoria and Agrimonia procera. A total of 94 herbal samples extracted with 40% aqueous ethanol were analyzed using ultrahigh-performance liquid chromatography and high-resolution tandem mass spectrometry and simultaneously tested against selected Gram-positive, Gram-negative, and anaerobic bacteria and yeasts. Targeted screening of bioactive polyphenols revealed significant differences between the agrimony species, with phloridzin and orientin/isoorientin identified as new potential chemotaxonomic markers. Notable differences were also observed between roots and aerial parts. Postharvest processing, particularly drying, proved to be another important factor, reducing the overall polyphenol content compared to fresh-frozen plant material. Although all extracts exhibited strong activity, especially against Gram-positive bacteria, the highest antimicrobial potential was observed in roots extracts rich in procyanidins and catechins. The findings of this study enhance the understanding of agrimony phytochemistry and its variability, thereby supporting the effective production of medicinal preparations with the desired therapeutic effects.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10611 - Plant sciences, botany

Projekt

<a href="/cs/project/LX22NPO5103" target="_blank" >LX22NPO5103: Národní institut virologie a bakteriologie</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chemistry and Biodiversity

ISSN

1612-1872

e-ISSN

1612-1880

Svazek periodika

22

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

15

Strana od-do

"e01283"

Kód UT WoS článku

001546177200001

EID výsledku v databázi Scopus

2-s2.0-105012739905