Tea Prepared from Dried Cannabis: What Do We Drink?
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F24%3A43929877" target="_blank" >RIV/60461373:22330/24:43929877 - isvavai.cz</a>
Výsledek na webu
<a href="https://pubs.acs.org/doi/10.1021/acs.jafc.4c05940" target="_blank" >https://pubs.acs.org/doi/10.1021/acs.jafc.4c05940</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acs.jafc.4c05940" target="_blank" >10.1021/acs.jafc.4c05940</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Tea Prepared from Dried Cannabis: What Do We Drink?
Popis výsledku v původním jazyce
Besides many other uses, dried Cannabis may be used for "tea" preparation. This study focused on a comprehensive characterization of an aqueous infusion prepared according to a common practice from three fairly different Cannabis cultivars. The transfer of 42 phytocannabinoids and 12 major bioactive compounds (flavonoids) into the infusion was investigated using UHPLC-HRMS/MS. Phytocannabinoid acids were transferred generally in a higher extent compared to their counterparts; in the case of Delta(9)-THC, it was only in the range of 0.4-1.9% of content in the Cannabis used. A dramatic increase of phytocannabinoids, mainly of the neutral species, occurred when cream was added during steeping, and the transfer of Delta(9)-THC into "tea" achieved a range of 53-64%. Under such conditions, drinking a 250 mL cup of such tea by a 70 kg person might lead to multiple exceedance of the Acute Reference Dose (ARfD), 1 mu g/kg b.w., even in the case when using hemp with a Delta(9)-THC content below 1% in dry weight for preparation.
Název v anglickém jazyce
Tea Prepared from Dried Cannabis: What Do We Drink?
Popis výsledku anglicky
Besides many other uses, dried Cannabis may be used for "tea" preparation. This study focused on a comprehensive characterization of an aqueous infusion prepared according to a common practice from three fairly different Cannabis cultivars. The transfer of 42 phytocannabinoids and 12 major bioactive compounds (flavonoids) into the infusion was investigated using UHPLC-HRMS/MS. Phytocannabinoid acids were transferred generally in a higher extent compared to their counterparts; in the case of Delta(9)-THC, it was only in the range of 0.4-1.9% of content in the Cannabis used. A dramatic increase of phytocannabinoids, mainly of the neutral species, occurred when cream was added during steeping, and the transfer of Delta(9)-THC into "tea" achieved a range of 53-64%. Under such conditions, drinking a 250 mL cup of such tea by a 70 kg person might lead to multiple exceedance of the Acute Reference Dose (ARfD), 1 mu g/kg b.w., even in the case when using hemp with a Delta(9)-THC content below 1% in dry weight for preparation.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
21101 - Food and beverages
Návaznosti výsledku
Projekt
<a href="/cs/project/LM2023064" target="_blank" >LM2023064: Infrastruktura pro propagaci metrologie v potravinářství a výživě v České republice</a><br>
Návaznosti
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Ostatní
Rok uplatnění
2024
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
ISSN
0021-8561
e-ISSN
1520-5118
Svazek periodika
72
Číslo periodika v rámci svazku
SEP 2024
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
12
Strana od-do
"21254−21265"
Kód UT WoS článku
001312730800001
EID výsledku v databázi Scopus
2-s2.0-85204245348