Quality and safety assessment of hemp-based food products: Insights into seeds, flours, and oils

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F25%3A43933111" target="_blank" >RIV/60461373:22330/25:43933111 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0889157525011536?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0889157525011536?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jfca.2025.108337" target="_blank" >10.1016/j.jfca.2025.108337</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Quality and safety assessment of hemp-based food products: Insights into seeds, flours, and oils

Popis výsledku v původním jazyce

The demand for hemp-derived food products, including oils, seeds, and flours, is growing because of their presumed nutritional benefits. However, concerns remain regarding the (unintentional) presence of psychotropic phytocannabinoids such as Δ⁹-tetrahydrocannabinol (Δ⁹-THC), even in products made from low-THC cultivars. This study presents a comprehensive analysis of 86 hemp food products purchased across the European market between 2022 and 2024. Using UHPLC-HRMS/MS, targeted analysis of 47 phytocannabinoids and 52 polyphenols was performed to assess both hazardous and health-promoting compounds. Phytocannabinoids, including trans-Δ⁹-THC, cis-Δ⁹-THC, and their precursor Δ⁹-THCA, were frequently quantified, especially in hemp seed oils. In several cases, calculated Δ⁹-THC intake exceeded the acute reference dose (ARfD) for a 70 kg adult after a standard serving, raising concerns about consumer safety, particularly for products labeled as &apos;THC-free&apos;. A shift toward lower Δ⁹-THC was observed in samples collected after the 2023 EU regulation setting maximum limits for this psychotropic compound. In addition to phytocannabinoids, polyphenols were quantified in all product types, with hemp seed flours showing the greatest diversity and highest concentrations of these bioactive secondary metabolites. In hemp oils, cannflavins A and B, unique lipophilic prenylflavonoids of Cannabis sativa L., were dominant. These findings highlight the value of advanced analytical approaches for characterization and quality control of hemp based foods. © 2025

Název v anglickém jazyce

Quality and safety assessment of hemp-based food products: Insights into seeds, flours, and oils

Popis výsledku anglicky

The demand for hemp-derived food products, including oils, seeds, and flours, is growing because of their presumed nutritional benefits. However, concerns remain regarding the (unintentional) presence of psychotropic phytocannabinoids such as Δ⁹-tetrahydrocannabinol (Δ⁹-THC), even in products made from low-THC cultivars. This study presents a comprehensive analysis of 86 hemp food products purchased across the European market between 2022 and 2024. Using UHPLC-HRMS/MS, targeted analysis of 47 phytocannabinoids and 52 polyphenols was performed to assess both hazardous and health-promoting compounds. Phytocannabinoids, including trans-Δ⁹-THC, cis-Δ⁹-THC, and their precursor Δ⁹-THCA, were frequently quantified, especially in hemp seed oils. In several cases, calculated Δ⁹-THC intake exceeded the acute reference dose (ARfD) for a 70 kg adult after a standard serving, raising concerns about consumer safety, particularly for products labeled as &apos;THC-free&apos;. A shift toward lower Δ⁹-THC was observed in samples collected after the 2023 EU regulation setting maximum limits for this psychotropic compound. In addition to phytocannabinoids, polyphenols were quantified in all product types, with hemp seed flours showing the greatest diversity and highest concentrations of these bioactive secondary metabolites. In hemp oils, cannflavins A and B, unique lipophilic prenylflavonoids of Cannabis sativa L., were dominant. These findings highlight the value of advanced analytical approaches for characterization and quality control of hemp based foods. © 2025

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40500 - Other agricultural sciences

Projekt

<a href="/cs/project/GA22-20860S" target="_blank" >GA22-20860S: Protizánětlivé účinky bioaktivních sloučenin izolovaných z Cannabis sativa L.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF FOOD COMPOSITION AND ANALYSIS

ISSN

0889-1575

e-ISSN

—

Svazek periodika

148

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

12

Strana od-do

nestránkováno

Kód UT WoS článku

001583109200002

EID výsledku v databázi Scopus

2-s2.0-105016663358