SPECIES TRANSPORT IMMERSED BOUNDARY SOLVER FOR QCM BIOSENSOR: INITIAL DEVELOPMENTS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F25%3A43933609" target="_blank" >RIV/60461373:22340/25:43933609 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.14311/TPFM.2025.030" target="_blank" >https://doi.org/10.14311/TPFM.2025.030</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.14311/TPFM.2025.030" target="_blank" >10.14311/TPFM.2025.030</a>

Jazyk výsledku

angličtina

Název v původním jazyce

SPECIES TRANSPORT IMMERSED BOUNDARY SOLVER FOR QCM BIOSENSOR: INITIAL DEVELOPMENTS

Popis výsledku v původním jazyce

Detection of life-threatening pathogens in water can be done by Quartz Crystal Microbalance (QCM) biosensors. The pathogenic species get trapped at the crystal surface leading to a measurable change in the crystal resonant frequency. As a microfluidic device, QCM operates under diffusion-limited conditions and in its current design, most of the analyte is trapped in regions with no or limited crystal sensitivity. Our long term goal is to improve the QCM sensor sensitivity through optimization of its geometry. The optimization will leverage the immersed boundary method to mitigate the need of creating a separate mesh for each tested design. The device performance will be evaluated by simulating the analyte transport in the sensor. In this contribution, we present the development and verification of a mass-preserving flux correction at the immersed boundary, which is the basis of the required transient solver for analyte transport in the presence of immersed boundaries.

Název v anglickém jazyce

SPECIES TRANSPORT IMMERSED BOUNDARY SOLVER FOR QCM BIOSENSOR: INITIAL DEVELOPMENTS

Popis výsledku anglicky

Detection of life-threatening pathogens in water can be done by Quartz Crystal Microbalance (QCM) biosensors. The pathogenic species get trapped at the crystal surface leading to a measurable change in the crystal resonant frequency. As a microfluidic device, QCM operates under diffusion-limited conditions and in its current design, most of the analyte is trapped in regions with no or limited crystal sensitivity. Our long term goal is to improve the QCM sensor sensitivity through optimization of its geometry. The optimization will leverage the immersed boundary method to mitigate the need of creating a separate mesh for each tested design. The device performance will be evaluated by simulating the analyte transport in the sensor. In this contribution, we present the development and verification of a mass-preserving flux correction at the immersed boundary, which is the basis of the required transient solver for analyte transport in the presence of immersed boundaries.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

10102 - Applied mathematics

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Topical Problems of Fluid Mechanics 2025

ISBN

978-80-87012-05-5

ISSN

2336-5781

e-ISSN

—

Počet stran výsledku

8

Strana od-do

225-232

Název nakladatele

Ústav termomechaniky AV ČR, v.v.i.

Místo vydání

Praha

Místo konání akce

Praha

Datum konání akce

12. 2. 2025

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

001597458700030