Comparative Measurements of Total Body Water in Healthy Volunteers by On-line Breath Deuterium Measurement and other Near-subject Methods.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F02%3A54030039" target="_blank" >RIV/61388955:_____/02:54030039 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Comparative Measurements of Total Body Water in Healthy Volunteers by On-line Breath Deuterium Measurement and other Near-subject Methods.

Popis výsledku v původním jazyce

Background: Accurate and rapid determination of total body water (TBW), a fundamental component of body composition, is a desirable goal in the study of physiology and the management of many medical conditions. We have developed a new breath test, usingFlowing-afterglow mass spectrometry (FA-MS) and deuterium dilution, which enables the immediate determination of TBW from single exhalations. Objective: To demonstrate the efficacy of the new FA-MS method in determining TBW in healthy subjects, and compare the results obtained with those from multifrequency bioimpedance analysis (BIA) and published regression equations. Design: Following baseline measurement of breath deuterium abundance (FA-MS), 24 healthy subjects took 0.3g/kg body weight D2O. A second breath sample was taken after two hours to measure the increase in deuterium and thus calculate TBW. BIA was carried out using a Xitron Hydra (4200). Methods were compared using Pearson correlation and Bland-Altman analyses.

Název v anglickém jazyce

Comparative Measurements of Total Body Water in Healthy Volunteers by On-line Breath Deuterium Measurement and other Near-subject Methods.

Popis výsledku anglicky

Background: Accurate and rapid determination of total body water (TBW), a fundamental component of body composition, is a desirable goal in the study of physiology and the management of many medical conditions. We have developed a new breath test, usingFlowing-afterglow mass spectrometry (FA-MS) and deuterium dilution, which enables the immediate determination of TBW from single exhalations. Objective: To demonstrate the efficacy of the new FA-MS method in determining TBW in healthy subjects, and compare the results obtained with those from multifrequency bioimpedance analysis (BIA) and published regression equations. Design: Following baseline measurement of breath deuterium abundance (FA-MS), 24 healthy subjects took 0.3g/kg body weight D2O. A second breath sample was taken after two hours to measure the increase in deuterium and thus calculate TBW. BIA was carried out using a Xitron Hydra (4200). Methods were compared using Pearson correlation and Bland-Altman analyses.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CF - Fyzikální chemie a teoretická chemie

OECD FORD obor

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Projekt

<a href="/cs/project/GA203%2F00%2F0632" target="_blank" >GA203/00/0632: Chemie iontů v plynné fázi a ve srážkách s povrchy</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2002

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

American Journal of Clinical Nutrition

ISSN

0002-9165

e-ISSN

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Svazek periodika

76

Číslo periodika v rámci svazku

N/A

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

1295-1301

Kód UT WoS článku

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EID výsledku v databázi Scopus

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