Minimising the Effects of Isobaric Product Ions in SIFT-MS Quantification of Acetaldehyde, Dimethyl Sulphide and Carbon Dioxide

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F13%3A00397544" target="_blank" >RIV/61388955:_____/13:00397544 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Minimising the Effects of Isobaric Product Ions in SIFT-MS Quantification of Acetaldehyde, Dimethyl Sulphide and Carbon Dioxide

Popis výsledku v původním jazyce

Analyses of the headspace of cell cultures using selected ion flow tube mass spectrometry, SIFT-MS, over the last few years have usually revealed the simultaneous presence of acetaldehyde, AA, and carbon dioxide, CO2. The characteristic primary product ions of reactions of the H3O+ ions with these compounds are at m/z 45, 63 and 81 for AA and m/z 63 for CO2. Recently, the presence of dimethyl sulphide, DMS, reaction of which with H3O+ ions also results in product ions at m/z 63 and 81, has also been detected in mammalian cell and bacterial cell culture headspace. The challenge now is to facilitate quantification of AA, DMS and CO2 when they coexist in humid air samples. Hence, an assessment has been made of the ion chemistry of H3O+ and NO+ with AA, DMS and CO2 in order to seek the appropriate procedures for their analyses by SIFT-MS. Thus, appropriate analytical reactions have been identified and kinetics library entries have been constructed for the analyses of these three compounds.

Název v anglickém jazyce

Minimising the Effects of Isobaric Product Ions in SIFT-MS Quantification of Acetaldehyde, Dimethyl Sulphide and Carbon Dioxide

Popis výsledku anglicky

Analyses of the headspace of cell cultures using selected ion flow tube mass spectrometry, SIFT-MS, over the last few years have usually revealed the simultaneous presence of acetaldehyde, AA, and carbon dioxide, CO2. The characteristic primary product ions of reactions of the H3O+ ions with these compounds are at m/z 45, 63 and 81 for AA and m/z 63 for CO2. Recently, the presence of dimethyl sulphide, DMS, reaction of which with H3O+ ions also results in product ions at m/z 63 and 81, has also been detected in mammalian cell and bacterial cell culture headspace. The challenge now is to facilitate quantification of AA, DMS and CO2 when they coexist in humid air samples. Hence, an assessment has been made of the ion chemistry of H3O+ and NO+ with AA, DMS and CO2 in order to seek the appropriate procedures for their analyses by SIFT-MS. Thus, appropriate analytical reactions have been identified and kinetics library entries have been constructed for the analyses of these three compounds.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Current Analytical Chemistry

ISSN

1573-4110

e-ISSN

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Svazek periodika

9

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

550-557

Kód UT WoS článku

000324493100004

EID výsledku v databázi Scopus

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