Biomedical Applications of Acridines: Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F17%3A00483977" target="_blank" >RIV/61388963:_____/17:00483977 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/978-3-319-63953-6" target="_blank" >http://dx.doi.org/10.1007/978-3-319-63953-6</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/978-3-319-63953-6" target="_blank" >10.1007/978-3-319-63953-6</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Biomedical Applications of Acridines: Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases

Popis výsledku v původním jazyce

This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents structures of acridines with nucleic acids and proteins and compares them with the native structures. Furthermore, the book presents modern methods of acridine synthesis,ncomparing them with the most useful conventional methods. Acridines interact with both nucleic acids and proteins, and due to their direct interactions with various enzymes, they can be suitable for the treatment of neurodegenerative diseases, inflammation, immunological disorders, and protozoal diseases. The characteristic spectral properties of acridines can be employed in labeling proteins, nucleic acids, lipids, and even cells and their compartments. Moreover, they can be applied in photodynamic therapy.

Název v anglickém jazyce

Biomedical Applications of Acridines: Derivatives, Syntheses, Properties and Biological Activities with a Focus on Neurodegenerative Diseases

Popis výsledku anglicky

This book describes applications of acridines for the treatment of various neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, and various prion diseases, and discusses the potential of acridines in neuro-regenerative medicine. Using modern data-mining software, it presents structures of acridines with nucleic acids and proteins and compares them with the native structures. Furthermore, the book presents modern methods of acridine synthesis,ncomparing them with the most useful conventional methods. Acridines interact with both nucleic acids and proteins, and due to their direct interactions with various enzymes, they can be suitable for the treatment of neurodegenerative diseases, inflammation, immunological disorders, and protozoal diseases. The characteristic spectral properties of acridines can be employed in labeling proteins, nucleic acids, lipids, and even cells and their compartments. Moreover, they can be applied in photodynamic therapy.

Druh

B - Odborná kniha

CEP obor

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OECD FORD obor

10401 - Organic chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

ISBN

978-3-319-63952-9

Počet stran knihy

237

Název nakladatele

Springer

Místo vydání

Cham

Kód UT WoS knihy

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