Identification of Lactobacillus proteins with different recognition patterns between immune rabbit sera and nonimmune mice or human sera

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F16%3A00460614" target="_blank" >RIV/61388971:_____/16:00460614 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1186/s12866-016-0631-9" target="_blank" >http://dx.doi.org/10.1186/s12866-016-0631-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s12866-016-0631-9" target="_blank" >10.1186/s12866-016-0631-9</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Identification of Lactobacillus proteins with different recognition patterns between immune rabbit sera and nonimmune mice or human sera

Popis výsledku v původním jazyce

The genus Lactobacillus belongs to a large heterogeneous group of low G + C Gram-positive anaerobic bacteria, which are frequently used as probiotics. The health-beneficial effects, in particular the immunomodulation effect, of probiotics depend on the strain and dose used. Strain variations may be related to diversity of the cell surface architecture of bacteria and the ability to express specific antigens or secrete compounds. The use of Lactobacillus as probiotic requires a comprehensive understanding of its effect on host immune system. To evaluate the potential immunoreactive properties of proteins isolated from four Lactobacillus strains: L. johnsonii 142 and L. johnsonii 151, L. rhamnosus LOCK 0900 and L. casei LOCK 0919, the polyclonal sera obtained from mouse and human have been tested as well as with sera from rabbits immunized with whole lactobacilli cells. /n

Název v anglickém jazyce

Identification of Lactobacillus proteins with different recognition patterns between immune rabbit sera and nonimmune mice or human sera

Popis výsledku anglicky

The genus Lactobacillus belongs to a large heterogeneous group of low G + C Gram-positive anaerobic bacteria, which are frequently used as probiotics. The health-beneficial effects, in particular the immunomodulation effect, of probiotics depend on the strain and dose used. Strain variations may be related to diversity of the cell surface architecture of bacteria and the ability to express specific antigens or secrete compounds. The use of Lactobacillus as probiotic requires a comprehensive understanding of its effect on host immune system. To evaluate the potential immunoreactive properties of proteins isolated from four Lactobacillus strains: L. johnsonii 142 and L. johnsonii 151, L. rhamnosus LOCK 0900 and L. casei LOCK 0919, the polyclonal sera obtained from mouse and human have been tested as well as with sera from rabbits immunized with whole lactobacilli cells. /n

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EC - Imunologie

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BMC Microbiology

ISSN

1471-2180

e-ISSN

—

Svazek periodika

16

Číslo periodika v rámci svazku

FEB 2016

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

11

Strana od-do

—

Kód UT WoS článku

000369696400002

EID výsledku v databázi Scopus

2-s2.0-84957599065