Cell adhesion on modified polyethylene.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389005%3A_____%2F02%3A49020015" target="_blank" >RIV/61389005:_____/02:49020015 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11120/02:00003598

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Cell adhesion on modified polyethylene.

Popis výsledku v původním jazyce

Polyethylene (PE) was irradited with 10 and 63 keV Ar+ ions to fluences of 1 x 10(17) to 3 x 10(19) m(-2) and then it was grafted with aminmoacid (alanine). The changes of surface polarity, electrical conductivity, and oxygen concentration were examinedon pristine, as-irradiated, and irradiated-grafted PE. The in vitro adhesion of mice fibroblasts on the modified PE was evaluated 24 hours after inoculation. It was proved that for the PE irradiated at 10 keV ion energy, the presence of chemically boundalanine increases cell adhesion and it homogenity. For PE irradiated with 63 keV ions, however, the alanine grafting leads to a reduction of the number of adhering cells. It was found thata rising surface polarity increases cell adhesion, but when its value is too high the cell adhesion starts to decrease. No correlation between electrical conductivity and cell adhesion was observed. In general, higher cell adhesion is observed on modified PE in comparison with pristine one.

Název v anglickém jazyce

Cell adhesion on modified polyethylene.

Popis výsledku anglicky

Polyethylene (PE) was irradited with 10 and 63 keV Ar+ ions to fluences of 1 x 10(17) to 3 x 10(19) m(-2) and then it was grafted with aminmoacid (alanine). The changes of surface polarity, electrical conductivity, and oxygen concentration were examinedon pristine, as-irradiated, and irradiated-grafted PE. The in vitro adhesion of mice fibroblasts on the modified PE was evaluated 24 hours after inoculation. It was proved that for the PE irradiated at 10 keV ion energy, the presence of chemically boundalanine increases cell adhesion and it homogenity. For PE irradiated with 63 keV ions, however, the alanine grafting leads to a reduction of the number of adhering cells. It was found thata rising surface polarity increases cell adhesion, but when its value is too high the cell adhesion starts to decrease. No correlation between electrical conductivity and cell adhesion was observed. In general, higher cell adhesion is observed on modified PE in comparison with pristine one.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BG - Jaderná, atomová a molekulová fyzika, urychlovače

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2002

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Materials Science

ISSN

0022-2461

e-ISSN

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Svazek periodika

37

Číslo periodika v rámci svazku

N/A

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

6

Strana od-do

1183-1188

Kód UT WoS článku

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EID výsledku v databázi Scopus

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