Well-defined linear and grafted poly(2-isopropenyl-2-oxazoline)s prepared via copper-mediated reversible-deactivation radical polymerization methods

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F20%3A00523715" target="_blank" >RIV/61389013:_____/20:00523715 - isvavai.cz</a>

Výsledek na webu

<a href="https://pubs.acs.org/doi/abs/10.1021/acs.macromol.9b02662" target="_blank" >https://pubs.acs.org/doi/abs/10.1021/acs.macromol.9b02662</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/acs.macromol.9b02662" target="_blank" >10.1021/acs.macromol.9b02662</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Well-defined linear and grafted poly(2-isopropenyl-2-oxazoline)s prepared via copper-mediated reversible-deactivation radical polymerization methods

Popis výsledku v původním jazyce

2-Isopropenyl-2-oxazoline (IPOx) is an important double functional monomer with multiple potential applications. However, until now, the attempts at reversible-deactivation radical polymerization (RDRP) of IPOx via its double bond have met with little success, leading to low conversions and high-dispersity products. Here, we demonstrate that IPOx can be polymerized through aqueous Cu(0)-mediated RDRP in a controlled way using the 2-chloropropionitrile/CuCl(CuCl2)/TPMA initiation and catalytic system and 0.67 M NaCl as a solvent. It is shown that the polymerization is highly sensitive to the initiator concentration and the CuCl/CuCl2 ratio. However, with careful optimization of the polymerization parameters, low-dispersity products can be obtained at quantitative conversions. The synthesized poly(IPOx) polymers were subsequently transformed into different ATRP macroinitiators by the reaction of the pendant 2-oxazoline units with 2-bromoisobutyric or 2-chloropropionic acid under optimized reaction conditions. Styrene and methyl methacrylate were then grafted as model monomers from these macroinitiators under ATRP conditions, confirming that defined poly(IPOx)-based graft copolymers with controlled grafting density and molecular weights of the poly(IPOx) backbone and of the grafts are accessible by the presented method. This provides a straightforward route to a new class of 2-oxazoline-based materials.

Název v anglickém jazyce

Well-defined linear and grafted poly(2-isopropenyl-2-oxazoline)s prepared via copper-mediated reversible-deactivation radical polymerization methods

Popis výsledku anglicky

2-Isopropenyl-2-oxazoline (IPOx) is an important double functional monomer with multiple potential applications. However, until now, the attempts at reversible-deactivation radical polymerization (RDRP) of IPOx via its double bond have met with little success, leading to low conversions and high-dispersity products. Here, we demonstrate that IPOx can be polymerized through aqueous Cu(0)-mediated RDRP in a controlled way using the 2-chloropropionitrile/CuCl(CuCl2)/TPMA initiation and catalytic system and 0.67 M NaCl as a solvent. It is shown that the polymerization is highly sensitive to the initiator concentration and the CuCl/CuCl2 ratio. However, with careful optimization of the polymerization parameters, low-dispersity products can be obtained at quantitative conversions. The synthesized poly(IPOx) polymers were subsequently transformed into different ATRP macroinitiators by the reaction of the pendant 2-oxazoline units with 2-bromoisobutyric or 2-chloropropionic acid under optimized reaction conditions. Styrene and methyl methacrylate were then grafted as model monomers from these macroinitiators under ATRP conditions, confirming that defined poly(IPOx)-based graft copolymers with controlled grafting density and molecular weights of the poly(IPOx) backbone and of the grafts are accessible by the presented method. This provides a straightforward route to a new class of 2-oxazoline-based materials.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/GA19-04047S" target="_blank" >GA19-04047S: Biochemické studie membránových raftů a imunoreceptorů založené na kopolymerech desintegrujících buněčné membrány</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Macromolecules

ISSN

0024-9297

e-ISSN

—

Svazek periodika

53

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

2077-2087

Kód UT WoS článku

000526395700020

EID výsledku v databázi Scopus

2-s2.0-85082335186